MSIsensor-RNA: Microsatellite Instability Detection for Bulk and Single-cell Gene Expression Data. [PDF]
Jia P+5 more
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Sex and outcomes of patients with microsatellite instability-high and <i>BRAF</i> V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors. [PDF]
Nasca V+35 more
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Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease. [PDF]
Kravchuk D+13 more
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Immune checkpoint inhibitor restores daily function in patient with microsatellite instability (MSI)-high advanced endometrial cancer and poor performance status. [PDF]
Matsui A+11 more
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Microsatellite instability and mismatch repair protein deficiency: equal predictive markers? [PDF]
Nádorvári ML+4 more
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Comprehensive Analysis of Microsatellite Instability in Canine Cancers: Implications for Comparative Oncology and Personalized Veterinary Medicine. [PDF]
Mazzone E, Aresu L.
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Microsatellite instability: an update
Archives of Toxicology, 2015Deficient DNA mismatch repair (MMR) results in a strong mutator phenotype known as microsatellite instability (MSI), which is a hallmark of Lynch syndrome-associated cancers. MSI is characterized by length alterations within simple repeated sequences that are called microsatellites.
Kohzoh Imai, Hiroyuki Yamamoto
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Detection of Microsatellite Instability [PDF]
In 1993, three groups independently discovered that the lengths of microsatellites in tumors could vary from the normally constant pattern defined at birth (5-5) (see review in ref. 4). This discovery has been designated either microsatellite instability (MSI) or replication errors (RER).
James R. Eshleman+2 more
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