Results 41 to 50 of about 124,795 (370)
Evaluating histopathology transfer learning with ChampKit [PDF]
, 2022 Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell detection and microsatellite instability classification.
arxiv +1 more source
Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
BMC Cancer, 2022 Background As a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet activation. Activated platelets participate in the regulation of innate immune cells.
Xin Zhang +5 more
doaj +1 more source
Modified ResNet Model for MSI and MSS Classification of Gastrointestinal Cancer [PDF]
arXiv, 2022 In this work, a modified ResNet model is proposed for the classification of Microsatellite instability(MSI) and Microsatellite stability(MSS) of gastrointestinal cancer. The performance of this model is analyzed and compared with existing models. The proposed model surpassed the existing models with an accuracy of 0.8981 and F1 score of 0.9178.
arxiv
Journal of Hematology & Oncology, 2019 Immunotherapies have led to substantial changes in cancer treatment and have been a persistently popular topic in cancer research because they tremendously improve the efficacy of treatment and survival of individuals with various cancer types.
Pengfei Zhao +3 more
doaj +1 more source
Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters. [PDF]
PLoS ONE, 2015 Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes, most frequently MLH1 and MSH2. Recently, MMR-deficient crypt foci (MMR-DCF) have been identified as a novel lesion which occurs at high frequency in the intestinal mucosa ...
Laura Staffa +11 more
doaj +1 more source
A Method for Improving the Detection Accura-cy of MSIsensor Based on Downsampling [PDF]
arXiv, 2023 Motivation: Microsatellite instability (MSI) is a cancer biomarker associated with cancer prognosis and chemotherapy sensitivity. Since the discovery of MSI, polymerase chain reaction (PCR)-based testing has been considered the gold standard for MSI detection.
arxiv
IJU Case Reports, 2023 Introduction Advanced adrenocortical carcinoma has a poor prognosis and is treated with chemotherapy that includes mitotane with etoposide, doxorubicin, and cisplatin as first‐line therapy.
Masaya Senda +5 more
doaj +1 more source
MAg: a simple learning-based patient-level aggregation method for detecting microsatellite instability from whole-slide images [PDF]
arXiv, 2022 The prediction of microsatellite instability (MSI) and microsatellite stability (MSS) is essential in predicting both the treatment response and prognosis of gastrointestinal cancer. In clinical practice, a universal MSI testing is recommended, but the accessibility of such a test is limited.
arxiv
Testing for lynch syndrome in people with endometrial cancer using immunohistochemistry and microsatellite instability-based testing strategies – a systematic review of test accuracy [PDF]
, 2021 Background Lynch syndrome is an inherited genetic condition that is associated with an increased risk of cancer, including endometrial and colorectal cancer.
Al-Khudairy, Lena +6 more
core +2 more sources