Results 151 to 160 of about 57,676 (330)

Development and characterization of highly polymorphic long TC repeat microsatellite markers for genetic analysis of peanut [PDF]

, 2012
Selma E Macedo, Márcio de Carvalho Moretzsohn, Soraya C. M. Leal‐Bertioli, Dione MT Alves, Ediene G Gouvea, Vânia Azevedo, David J. Bertioli   +6 more
openalex   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

Animal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez, Anthony J. Clemento, Juliette E. Linossier, Daniel E. Crocker, Daniel P. Costa, Colleen Reichmuth, John Carlos Garza   +6 more
wiley   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Decoding Senescence‐Driven Heterogeneity in Early‐Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Cancer Science, EarlyView.
We uncovered pronounced and heterogeneous tumor senescence in EOCRC, independent of age. By integrating multi‐omics and single‐cell analyses, we developed EO‐Senscore, a prognostic tool that stratifies patients by immune phenotype and therapy response, enabling precision treatment using immunotherapy or senolytic agents. ABSTRACT Early‐onset colorectal
Du Cai, Mingru Mai, Rende Huang, Haoning Qi, Xingzhi Feng, Qianling Gao, Yinmeng Zhang, Chenghang Li, Xiaojian Wu, Yize Mao, Zihuan Yang, Feng Gao   +11 more
wiley   +1 more source

Vitamin D Receptor Microsatellite Repeats in the 3’untranslated region: Relation to Early Onset Breast Cancer among Pakistani Women

, 2022
Mehir un Nisa Iqbal, Rabiya Ali, Syed Amir Maqbool, Taseer Ahmed Khan   +3 more
openalex   +2 more sources

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

Clinical Genetics, EarlyView.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson, Daniel E. McGinn, T. Blaine Crowley, Lydia Rockart, Audrey Green, Victoria Giunta, Oanh Tran, Daniella Miller, Jeroen Breckpot, Ann Swillen, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Federica Pulvirenti, Bruno Marino, Beverly S. Emanuel, Elaine H. Zackai, Zhengdong D. Zhang, Elizabeth Goldmuntz, Erik Boot, Anne S. Bassett, Bernice E. Morrow, Donna M. McDonald‐McGinn   +22 more
wiley   +1 more source

A Conceptual Framework and Methods for Studying the Connectivity of Fishes

Fish and Fisheries, EarlyView.
ABSTRACT Connectivity is a multifaceted concept that has important implications for the management and conservation of marine and freshwater fishes. We developed a conceptual framework that encompasses multiple, interrelated categories of connectedness, including landscape (e.g., structural, functional) connectivity and ecological (e.g., trophic ...
Jordanna N. Bergman, Jessica A. Robichaud, Jasper McCutcheon, Michael T. Booth, Brendan Campbell, Grace A. Casselberry, Cienna R. Cooper, Bronwyn M. Gillanders, Lucas P. Griffin, Edward Hale, Luc LaRochelle, Karen J. Murchie, Mary Peacock, Reid G. Swanson, Simon D. Stewart, Ryan. J. Woodland, Daniel P. Zielinski, Steven J. Cooke, Morgan L. Piczak   +18 more
wiley   +1 more source

Compound‐Specific Stable Isotope Analysis Reveals Population‐Specific Differences in Chinook Salmon Trophic Level and Basal Resource Use in the Northeast Pacific

Fisheries Oceanography, EarlyView.
ABSTRACT Chinook salmon exhibit far‐flung and disparate population‐specific marine migrations that have made it difficult to assess their trophic ecology. In this study, we collected returning and resident subadult Fraser River Chinook salmon in 2018 and 2019 from population groups with different known run‐timings (spring, summer, and fall) and marine ...
Jacob E. Lerner, Brian P. V. Hunt
wiley   +1 more source

Microsatellite repeat dynamics in mitochondrial genomes of phytopathogenic fungi: frequency and distribution in the genic and intergenic regions [PDF]

, 2012
Sahil Mahfooz, Pallavi Singh, Deepak Kumar Maurya, Mahesh C. Yadav, Azram Tahoor, Harmesh Sahay, Arpita Srivastava, Anil Prakash   +7 more
openalex   +1 more source

Establishment of a broad-spectrum marker for er1/PsMLO1 powdery mildew resistance in pea (Pisum sativum L.) [PDF]

, 2018
O oídio, causado pelo fungo ascomycete Erysiphe pisi Syd, é uma das doenças mais importantes que afectam a produção de ervilha (Pisum sativum L.) em Portugal e em países por todo o mundo (Sousa, 1999). Esta doença prospera em climas húmidos temperados
Cardoso, André Filipe Dias Almeida
core