Results 191 to 200 of about 55,724 (327)
Isolation and identification of microsatellite repeat motifs from the Epinephelus fuscoguttatus genome [PDF]
, 2013 Azinuddin Ahmad Mokhtar Mohd +3 more
openalex +1 more source
Application of msh3 immunohistochemistry and tetranucleotide microsatellite analysis to identify Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) in colorectal tumours [PDF]
, 2020 Alexandra Kang +4 more
openalex +1 more source
Biological Reviews, EarlyView.ABSTRACT The global proliferation of dams has altered flow and sediment regimes in rivers, presenting a major threat to freshwater biodiversity. Diadromous species, such as fishes, decapod crustaceans and gastropods, are particularly susceptible to fragmentation because dams obstruct their breeding migrations between coastal waters and rivers. Although
Jeffery C. F. Chan +3 more
wiley +1 more source
Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders [PDF]
, 2014 John D. Cleary, Laura P.W. Ranum
openalex +1 more source
The pace and shape of ant ageing
Biological Reviews, EarlyView.ABSTRACT Ants have been proposed as good models to study ageing and the effects of extrinsic mortality because of their long lifespans and plasticity of ageing within species. We discuss how age‐dependent extrinsic mortality might influence queen lifespan, and how the effect of age‐independent extrinsic mortality needs further study, accounting for ...
Luisa M. Jaimes‐Nino, Jan Oettler
wiley +1 more source
Microsatellite repeat motif and amplicon length affect amplification success of degraded faecal DNA [PDF]
, 2014 Alida de Flamingh +2 more
openalex +1 more source
Cancer Science, EarlyView.We successfully integrated the C‐CAT repository and QI datasets to compare real‐world outcomes of gene‐matched therapy and non‐gene‐matched therapy, showing no significant difference in 2‐year overall survival between the groups. Potential reasons for this discrepancy from previous trials include differences in cancer types, comprehensive genomic ...
Taisuke Ishii +7 more
wiley +1 more source
Cancer Science, EarlyView.We clarified the utility and challenges of in‐house comprehensive genomic profiling (CGP) testing in lung cancer care. ABSTRACT Comprehensive genomic profiling (CGP) is useful for optimizing targeted therapy and immunotherapy strategies for thoracic malignancies. This study aimed to evaluate the clinical utility and diagnostic complementarity of the in‐
Hatsuyo Takaoka +25 more
wiley +1 more source
Challenges and Pitfalls in Diagnosing Twins With Discordant BWS Phenotype
Clinical Genetics, EarlyView.Accurately diagnosing Beckwith–Wiedemann syndrome (BWS) in twins with discordant phenotypes is essential for personalized oncological monitoring and management. It is advisable to test both twins, even without phenotypic expression, and incorporate prenatal factors like assisted reproduction technologies and twin pregnancies into the diagnostic BWS ...
Iacopo Bellani +8 more
wiley +1 more source
Cell Proliferation, EarlyView.To identify genetic events that can lead to tumour death once either MLH1 or TP53 is mutated, a genome‐wide genetic screening was performed, uncovering a list of putative hits. Synthetic lethal interactions were validated either genetically or chemically by using small molecules that inhibit these genes either in vitro and in vivo.
Rivki Cashman +12 more
wiley +1 more source