Results 311 to 320 of about 57,676 (330)

Analysis of microsatellite repeats in pediatric brain tumors

Cancer Genetics and Cytogenetics, 1995
Tumorigenesis has been shown to proceed through a series of genetic alterations involving protooncogenes and tumor suppressor genes. However, investigation of genomic instability of microsatellites has disclosed a new mechanism for human carcinogenesis, which is involved not only in hereditary nonpolyposis colon cancer (HNPCC) but also in a number of ...
N, Amariglio, E, Friedman, O, Mor, H, Stiebel, C, Phelan, P, Collins, M, Nordenskjold, F, Brok-Simoni, G, Rechavi   +8 more
openaire   +2 more sources

Microsatellite Repeats: Canaries in the Coalmine

2013
Our genomes are much more dynamic than we ever imagined, creating variation that is good for evolution, but often bad for the individual. Microsatellite repeats constitute especially plastic genomic elements that can operate as rheostats to fine-tune gene function.
Nimrat Chatterjee, Beatriz A. Santillan, John H. Wilson   +2 more
openaire   +1 more source

Molecular characterization of GATA/GACA microsatellite repeats in tomato

Genome, 1997
Microsatellite repeats like GATA or GACA display a degree of variability that allows their use in cultivar identification. Southern hybridization with oligonucleotide probes complementary to these microsatellites were used for the detection of polymorphisms.
Vosman, B., Arens, P.F.P.
openaire   +3 more sources

Instability of short tandem repeats (microsatellites) in human cancers

Nature Genetics, 1994
The allele sizes of polymorphic microsatellite repeats in DNA from human cancers were compared to normal DNA from the same patients. In 16 out of 196 paired samples (8%), we found evidence of an extra allele of a different size in the tumour which was not present in the normal DNA.
Wooster, R., Cleton-Jansen, A. M., Collins, N., Mangion, J., Cornelis, R. S., Cooper, C. S., Gusterson, B. A., Ponder, B. A.J., von Deimling, A., Wiestler, O. D., Cornelisse, C. J., Devilee, P., Stratton, M. R.   +12 more
openaire   +3 more sources

Convergent transcription through microsatellite repeat tracts induces cell death

Molecular Biology Reports, 2014
Microsatellite sequences, composed of short tandem repeats and randomly distributed in human genome, can become unstable during various DNA metabolic processes. Expansions of CAG, GAA, CGG and CCTG repeats located in specific genes are responsible for several human disorders.
William Y, Lin, Yunfu, Lin, John H, Wilson   +2 more
openaire   +2 more sources

Microsatellite Testing Short Tandem Repeat Profile Generation

2012
The need for more and more information from less and less DNA sample, rapidly, has led laboratories from the use of minisatellites (variable number of tandem repeats, VNTRs) for human identification (HID) to the use of microsatellites (short tandem repeats, STRs).
Robin DeVille Guidry, Laura Gahn
openaire   +1 more source

An equine tetranucleotide repeat: microsatellite MPZ001

Animal Genetics, 1994
Breen M., Downs P., Irvin Z., Bell K.
openaire   +3 more sources

Twenty‐one new equine dinucleotide repeat microsatellites

Animal Genetics, 2000
M C, Roberts, J, Murtaugh, S J, Valberg, J R, Mickelson, L J, Alexander   +4 more
openaire   +2 more sources

Instability of short tandem repeats (microsatellites) in human gliomas.

Journal of neurosurgical sciences, 1994
Microsatellite instability implying multiple replication errors (RER) characterizes a proportion of familial and sporadic carcinomas. The purpose of this report is to analyze whether microsatellite instability occurred during the development of human gliomas.We checked prospectively 16 central nervous system tumors, including 10 glioblastomas and 6 ...
van de Kelft, Erik, Verlooy, Jan
openaire   +2 more sources

Microsatellite repeat polymorphism at the D13S197 locus

Human Molecular Genetics, 1993
H K, Hong, R, Giorda, L M, Yu, M, Trucco, A, Chakravarti   +4 more
openaire   +2 more sources