Results 131 to 140 of about 2,794,950 (328)

THE MICROSCOPE AND LIFE [PDF]

open access: yesSchool Science and Mathematics, 1903
n ...
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Progress on testing Lorentz symmetry with MICROSCOPE

open access: yes, 2017
The Weak Equivalence Principle (WEP) and the local Lorentz invariance (LLI) are two major assumptions of General Relativity (GR). The MICROSCOPE mission, currently operating, will perform a test of the WEP with a precision of $10^{-15}$.
Bars, H. Pihan-Le, Guerlin, C., Wolf, P.
core  

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Leeuwenhoek's microscope

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2011
Con frecuencia la Ciencia y la Técnica van de la mano. Casi todos los avances científicos han sido el resultado de nuevos avances técnicos. Esto es particularmente ilustrativo en lo referente al descubrimiento de la célula.
Garrido Garrido, Belén   +1 more
doaj  

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

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