Results 201 to 210 of about 2,869,633 (331)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Effects of Belatacept Therapy on Gene Expression Profiling and Rejection in Heart Transplant Recipients: A Molecular Microscope (MMDx) Evaluation [PDF]

open access: bronze
Daniel Oren   +22 more
openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

The Microscope and the Tubular System: Trend or Real Benefit in Lumbar Spinal Stenosis and Disc Herniation? [PDF]

open access: yesCureus
Sosa Najera A   +4 more
europepmc   +1 more source

Emittance Minimization for Aberration Correction I: Aberration correction of an electron microscope without knowing the aberration coefficients [PDF]

open access: green
Desheng Ma   +8 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells. [PDF]

open access: yesPharmacol Res Perspect
Li X   +8 more
europepmc   +1 more source

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