Results 51 to 60 of about 2,869,633 (331)

Strings and Branes under Microscope

open access: yes, 2003
It is shown that in the standard vacuum 5D Kaluza-Klein gravity there is wormhole-like solutions which look like strings attached to two D-branes. The asymptotical behaviour of the corresponding metric is investigated.Comment: comparison with known ...
Bertotti   +7 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Impact of minimally invasive root canal treatment on healing outcomes in a randomized clinical trial

open access: yesScientific Reports
Minimally invasive endodontic treatment has been an important topic of discussion in recent years, particularly in endodontics. This randomized prospective clinical trial aimed to assess outcomes after at least 2 years following two distinct root canal ...
Seung-Kyung Kwon   +3 more
doaj   +1 more source

Continuous Feature-Based Tracking of the Inner Ear for Robot-Assisted Microsurgery

open access: yesFrontiers in Surgery, 2021
Robotic systems for surgery of the inner ear must enable highly precise movement in relation to the patient. To allow for a suitable collaboration between surgeon and robot, these systems should not interrupt the surgical workflow and integrate well in ...
Christian Marzi   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Three-Dimensional Imaging in Stem Cell-Based Researches

open access: yesFrontiers in Veterinary Science, 2021
Stem cells have an important role in regenerative therapies, developmental biology studies and drug screening. Basic and translational research in stem cell technology needs more detailed imaging techniques.
Fariborz Nowzari   +13 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Black Hole Lattices Under the Microscope

open access: yes, 2018
It is known how to choose initial data for Einstein's equations describing an arbitrary number of black holes at a moment of time symmetry. This idea has been used to give insight into the cosmological averaging problem.
Bengtsson, Ingemar, Galstyan, Irina
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Les Formes du vivant

open access: yesImages Re-Vues, 2021
Scientists concerned with the visibility of natural manifestations quickly turned to mechanical recording instruments to create images of the observations gathered during their experiments. Adopted by modern science, microcinematography – the combination
Lydie Delahaye
doaj   +1 more source

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