Results 41 to 50 of about 3,665 (184)

Stimuli‐Responsive Silsesquioxane Nanozymes for Organocatalysis in Water and Prodrug Activation in Cells

Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.
Amino‐bearing silsesquioxanes are water‐stable nanozymes that exhibit aggregation‐ and disaggregation‐dependent catalysis and can be applied to intracellular prodrug activation for cancer therapy. ABSTRACT Synthetic nanozymes have emerged as promising alternatives to natural enzymes for catalytic and therapeutic applications, yet their limited ...
Rabia Zahid, Ariadna Lázaro, Guillermo Moreno‐Alcántar, María Sancho‐Albero, Pierre Picchetti   +4 more
wiley   +2 more sources

Ohmic heating dominates and ultrasound modulates aquafaba structure: A combined approach to design stable plant‐based emulsions

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study investigated the individual and combined effects of ohmic heating (OH, 20 and 40 V cm−1) and ultrasound (US, 425 and 850 W) on the chemical, physicochemical, and technological properties of chickpea aquafaba (AF) and its emulsions.
Débora Krichanã, Thaís Caroline Buttow Rigolon, Paula Zambe Azevedo, João Paulo de Melo Lins, Gabriel Oliveira Horta, Linamarys Aparecida de Oliveira Paulo, Márcia Cristina Teixeira Ribeiro Vidigal, Taline Amorim Santos, Isis Rodrigues Toledo Renhe, Jaqueline de Araújo Bezerra, Paulo César Stringheta, Evandro Martins, Pedro Henrique Campelo   +12 more
wiley   +1 more source

Altered cytoskeletal arrangement in induced pluripotent stem cells and motor neurons from patients with riboflavin transporter deficiency

Disease Models & Mechanisms, 2021
The cytoskeletal network plays a crucial role in the differentiation, morphogenesis, function and homeostasis of the nervous tissue, so that alterations in any of its components may lead to neurodegenerative diseases.
Alessia Niceforo, Chiara Marioli, Fiorella Colasuonno, Stefania Petrini, Keith Massey, Marco Tartaglia, Enrico Bertini, Sandra Moreno, Claudia Compagnucci   +8 more
doaj   +1 more source

Application of Ag‐Enriched Nanostructures Through Ga+ Irradiation of Silver Butyrate Films in Surface‐Enhanced Raman Spectroscopy (SERS)

Small Methods, EarlyView.
We report a direct‐writing method for patterning silver‐enriched nanostructures with dual functionality: High electrical conductivity, with a resistivity of 95 µΩ·cm, and strong SERS activity, achieving enhancement factors exceeding 107. This approach enables an easy and cost‐effective alternative for the production of microstructures with applications
Juan Ignacio Ocaña‐Parral, Lucía Herrer, Inés Tejedor, Alba Salvador‐Porroche, Sven Barth, Pilar Cea, Soraya Sangiao, José María De Teresa   +7 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Synthesis, Characterization, and Optical Properties of Undoped and Te‐Doped W(SxSe(1−x))2 and Core‐Shell WS2@W(SxSe(1−x))2 Nanotubes

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
W(SxSe1−x)2, Te:WSSe, and WS2@WSSe nanotubes were synthesized through controlled precursor composition. The W(SxSe1−x)2 and Te:WSSe nanotubes exhibit small‐diameter (<30 nm), high‐yield, and well‐defined excitonic transitions. Composition tuning via S/Se ratios increases interlayer spacing with higher Se content. The incorporation of Te remains limited
Philip Nathaniel Immanuel, Neena Prasad, Akshay Puravankara, Stepan Kusak, Rita Rosentsveig, Yishay Feldman, Anna Eden‐Kossoy, Ifat Kaplan‐Ashiri, Vojtech Kundrat, Raul Arenal, Reshef Tenne, Lena Yadgarov   +11 more
wiley   +1 more source

A produção do conhecimento engendrado pela base científica laboratorial: um estudo no laboratório central de microscopia eletrônica da Universidade Federal de Santa Catarina [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Programa de Pós-Graduação em Educação, Florianópolis, 2013.Esta tese apresenta os resultados de uma pesquisa cujo tema refere-se ao estudo das relações sociais que
Campana, Samya
core  

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Contribuição da Microscopia Confocal In Vivo para o Diagnóstico e Follow-Up de Neoplasias Conjuntivais Intraepiteliais

, 2014
Objectivo: Analisar o contributo da microscopia confocal in vivo para o diagnóstico efollow-up de neoplasias conjuntivais intraepiteliais. Métodos: Avaliámos 5 doentes com neoplasia conjuntival intraepitelial unilateral com o Heidelberg Retina Tomograph
Anjos, R, Santos, A, Maduro, V, Vieira, L, Martins, M   +4 more
core   +1 more source

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López, Jose I. Garcia‐Peiro, Felipe Hornos, Jose L. Hueso, Jesus Santamaria, J. Manuel Garcia‐Aznar   +5 more
wiley   +1 more source