Results 191 to 200 of about 277,529 (354)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Microscopic image dataset for air-permeability classification of patterned knitted fabrics. [PDF]

Sci Rep
Merkepçi M.
europepmc   +1 more source

The Presence of Selected Elements in the Microscopic Image of Pine Needles as an Effect of Cement and Lime Pressure within the Region of Białe Zagłębie (Central Europe). [PDF]

Toxics, 2021
Szwed M, Żukowski W, Kozłowski R.
europepmc   +1 more source

Microsphere-assistance in microscopic and confocal imaging [PDF]

Lucie Hüser, Sebastian Hagemeier, Tobias Pahl, Peter Lehmann   +3 more
openalex   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Consistency-Driven Dual-Teacher Framework for Semi-Supervised Zooplankton Microscopic Image Segmentation. [PDF]

J Imaging
Li Z, Wang Y, Yuan D, Qi Y, Song X.
europepmc   +1 more source

Supervised Automation of Cell Counting in Confocal Microscopic Cochlear Imaging Datasets Using Macro in Imaris [PDF]

Muhammad Taifur Rahman, Nashwaan Ali Khan, Mobin Ibne Mokbul, Ibrahim Razu, Shakila Mahmuda Fatima, Samia Sultana Lira, Cristina García–Cardona, Peter Eckard, Marlan R. Hansen   +8 more
openalex   +1 more source

A novel biotinylated lipid raft reporter for electron microscopic imaging of plasma membrane microdomains [PDF]

, 2012
Kimberly J. Krager, Mitul Sarkar, Erik Twait, Nancy L. Lill, John G. Koland   +4 more
openalex   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Research on Augmentation of Wood Microscopic Image Dataset Based on Generative Adversarial Networks. [PDF]

J Imaging
Xu S, Su H, Zhao L.
europepmc   +1 more source