Results 61 to 70 of about 277,529 (354)

Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network

Frontiers in Medicine, 2021
Clinically, red blood cell abnormalities are closely related to tumor diseases, red blood cell diseases, internal medicine, and other diseases. Red blood cell classification is the key to detecting red blood cell abnormalities. Traditional red blood cell
Weiqing Song, Pu Huang, Jing Wang, Yajuan Shen, Jian Zhang, Zhiming Lu, Dengwang Li, Danhua Liu   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Detection of structural similarity for multimodal microscopic image registration

, 2013
In this paper we propose a novel method to detect the structural similarity in registering color and confocal microscopic images. Our prior work [1] presented the basic idea of detecting the structural similarity of such images, which utilizes the ...
Martin Lackmann, Lv, Guohua, Lu, Guojun, Lackmann, Martin, Teng, Shyh, Guohua Lv, Guojun Lu, Shyh Wei Teng   +7 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Separating Particulate Matter From a Single Microscopic Image

, 2020
© 2020 IEEE.Particulate matter (PM) is the blend of various solid and liquid particles suspended in atmosphere. These submicron particles are imperceptible for usual hand-held camera photography, but become a great obstacle in microscopic imaging.
Tushar Sandhan, Choi, Jin Young, Sandhan, Tushar, Jin Young Choi   +3 more
core   +1 more source

Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming

Frontiers in Immunology, 2019
Recently, it has been described that programmed cell death protein 1 (PD-1) overexpressing melanoma cells are highly aggressive. However, until now it has not been defined which factors lead to the generation of PD-1 overexpressing subpopulations.
Edina Gyukity-Sebestyén, Edina Gyukity-Sebestyén, Mária Harmati, Mária Harmati, Gabriella Dobra, Gabriella Dobra, István B. Németh, Johanna Mihály, Ágnes Zvara, Éva Hunyadi-Gulyás, Róbert Katona, István Nagy, Péter Horváth, Árpád Bálind, Ábel Szkalisity, Mária Kovács, Mária Kovács, Tibor Pankotai, Barbara Borsos, Miklós Erdélyi, Zsolt Szegletes, Zoltán J. Veréb, Edit I. Buzás, Lajos Kemény, Tamás Bíró, Krisztina Buzás, Krisztina Buzás   +26 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Quantitative Analysis of Meteorite Elements Based on the Multidimensional Scaling–Back Propagation Neural Network Algorithm Combined with Raman Mapping-Assisted Micro-Laser Induced Breakdown Spectroscopy

Chemosensors, 2023
Meteorites are an essential reference for human exploration of the universe and its cosmic evolution and an essential research object for searching for extraterrestrial life. Ways to quickly identify and screen suspected meteorite samples have become the
Hongpeng Wang, Yingjian Xin, Peipei Fang, Yian Wang, Mingkang Duan, Wenming Wu, Ruidong Yang, Sicong Liu, Liang Zhang, Xiong Wan   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source