Results 161 to 170 of about 1,009,075 (346)

Construction of Biologic Microscopic Image Segmentation Model Based on Smoothing of Fourth-Order Partial Differential Equation [PDF]

, 2022
Ye Ma
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Docking problem between 3-dimensional electron microscopic image and atomic model : An approach to solution by molecular dynamics analysis

, 2003
Kazuki Noda, Takuo Yasunaga
openalex   +2 more sources

Two models based on local microscopic relaxations to explain long-term basic creep of concrete [PDF]

, 2018
Matthieu Vandamme
openalex   +1 more source

Microscopic and macroscopic traffic flow models including random accidents [PDF]

, 2021
Simone Göttlich, Thomas Schillinger
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Theoretical modeling of microscopic photothermal expansion and experimental study of photothermal microactuators

, 2009
Chao Liu, Zhang Dong-xian, Haijun Zhang, 浙江大学现代光学仪器国家重点实验室，杭州 310027   +3 more
openalex   +1 more source

Chemical freeze-out parameters at RHIC from microscopic model calculations [PDF]

, 2002
L.V. Bravina, E.E. Zabrodin, S.A. Bass, A. Faessler, C. Fuchs, M.I. Gorenstein, W. Greiner, S. Soff, H. Stöcker, H. Weber   +9 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A Mathematical Model to Simulate Glioma Growth and Radiotherapy at the Microscopic Level

, 2012
Alina Toma, Konstanze Holl‐Ulrich, Stefan Becker, Andreas Mang, Tina Anne Schütz, Matteo Mario Bonsanto, Volker Tronnier, Thorsten M. Buzug   +7 more
openalex   +2 more sources