Results 151 to 160 of about 1,011,329 (344)
Microscopic and macroscopic traffic flow models including random accidents [PDF]
, 2021 Simone Göttlich, Thomas Schillinger
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Microscopic modelling of boiling
, 2016 One of the main thermal-hydraulic challenges of LWR modelling is the prediction of boiling phenomena. This thesis describes numerical and analytical studies aimed at modelling the heat transfer and hydrodynamics of a single steam bubble during nucleate boiling of water, aiming both to improve our current understanding of the phenomena - of the ...
openaire +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Scientific ReportsThe Block Discrete Element Method is widely used in engineering research because it can accurately model fractured rock masses. However, the accuracy of simulations depends on selecting appropriate microscopic parameters, which cannot be directly ...
Yifan Jiang +7 more
doaj +1 more source
Do microscopic merging models reproduce the observed priority sharing ratio in congestion?
, 2009 Estelle Chevallier, Ludovic Leclercq
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Microscopic modeling of tunneling spectra in Bi$_2$Sr$_2$Ca$_2$Cu$_3$O$_{10+\delta}$ (Bi-2223) [PDF]
, 2013 Christophe Berthod +6 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source