Results 251 to 260 of about 1,009,075 (346)

Physical microscopic model of proteins under force. [PDF]

J Phys Chem B, 2012
Dokholyan NV.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Multiscale Modelling, Analysis and Simulation of Cancer Invasion Mediated by Bound and Soluble Enzymes. [PDF]

Bull Math Biol
Ptashnyk M, Venkataraman C.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Precise detection of Eimeria oocysts in sheep: a deep learning model based on microscopic images. [PDF]

Parasit Vectors
Liu L, Xie J, Qin H, Sui X, Zhang L.
europepmc   +1 more source

Relational Density Cosmology: A Unified Model from Microscopic Correlations to Cosmic Fate

lichao
openalex   +1 more source

Constitutive modelling and microscopic analysis of TC4 alloy sheet at elevated temperature

, 2019
Hui Wang, Kongxun Zhao, Xingrong Chu, Bing Zhao, Jun Gao   +4 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Force field sensitivity of ion occupancy in potassium channels. [PDF]

Biophys J
Mendoza Uriarte R, Roux B.
europepmc   +1 more source

An interface-based microscopic model for the failure analysis of masonry structures reinforced with timber retrofit solutions

Fabrizio Greco, Lorenzo Leonetti, Paolo Lonetti, Paolo Nevone Blasi, Arturo Pascuzzo, Giacinto Porco   +5 more
openalex   +2 more sources