Objective To compare the efficacy of abatacept to placebo for the treatment of relapsing, nonsevere granulomatosis with polyangiitis (GPA). Methods In this multicenter trial, eligible patients with relapsing, nonsevere GPA were randomized to receive abatacept 125 mg subcutaneously once a week or placebo, both together with prednisone 30 mg/day (or ...
Carol A. Langford +155 more
wiley +1 more source
Linked help from bacterial proteins drives autoantibody production in small vessel vasculitis. [PDF]
The small vessel vasculitides granulomatosis with polyangiitis (GPA) and microscopic polyangiitis are associated with autoantibodies to neutrophil cytoplasm antigens (ANCA), principally proteinase-3 (PR3) and myeloperoxidase (MPO).
Oliveira, DBG
core +1 more source
Fulminant Wegener's granulomatosis: A case report [PDF]
Introduction. Granulomatosis Wegener is anti-neutrophil cytoplasmic antibodies (ANCAs)-associated systemic vasculitis of unknown etiology. It is manifested as granulomatous necrotizing inflammation of the upper and lower parts of the respiratory tract,
Dinić Miroslav Ž. +3 more
core +1 more source
A Rare Case of Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis Presenting as Pyelonephritis [PDF]
Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV) is a condition affecting small and medium-sized vessels, predominantly impacting the kidneys.
Chetan Phadke, Shreeharsh Godbole
doaj +1 more source
ANCA Associated vasculitis- A case of microscopic polyangiitis with proliferative glomerulonephritis
R.C. Akshaya +3 more
openalex +1 more source
Long- term outcome of paediatric patients with ANCA vasculitis [PDF]
Background: Primary systemic vasculitis presenting in childhood is an uncommon but serious condition. As these patients transfer to adult clinics for continuing care, defining long term outcomes with emphasis on disease and treatment-related morbidity ...
Arulkumaran, N +6 more
core +3 more sources
Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial. [PDF]
BACKGROUND: Granulomatosis with polyangiitis (GPA, Wegener's) and microscopic polyangiitis (MPA) are small vessel vasculitides collectively referred to as anti-neutrophil cytoplasm antibody-associated vasculitis (AAV).
Clark, William F +13 more
core +4 more sources
Journal of Hospital Medicine, Volume 21, Issue 2, Page 200-204, February 2026.
Gurpreet Dhaliwal +4 more
wiley +1 more source
Microscopic Polyangiitis with Pulmonary Fibrosis: An Often-Recognized Manifestation of the Disease
Background. Microscopic polyangiitis (MPA) can manifest with atypical features such as pulmonary fibrosis and chronic obstructive pulmonary disease (COPD), which are atypical and unusual features of small vessel vasculitis. Case Presentation.
Liam M. Clifford +3 more
doaj +1 more source
Severe digital ischaemia treated with phosphodiesterase inhibitors [PDF]
published_or_final_versio
Cheung, GTY, Kumana, CR, Lau, CS
core +2 more sources

