Results 161 to 170 of about 14,703,710 (286)

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

open access: yesAdvanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial   +5 more
wiley   +1 more source

Microscopic Modeling of Traffic Within Freeway Lanes

open access: yes, 1995
Microscopic models provide an understanding of traffic operations at the level of passage of individual vehicles. Roadway performance can be ascertained by understanding how vehicles interact with each other. Cowan's M3 headway distribution models were
Bunker, Jonathan M.   +1 more
core  

Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment

open access: yesAdvanced Science, EarlyView.
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo   +15 more
wiley   +1 more source

A Lagrangian discretization multiagent approach for large-scale multimodal dynamic assignment [PDF]

open access: yes
This paper develops a Lagrangian discretization multiagent model for large-scale multimodal simulation and assignment. For road traffic flow modeling, we describe the dynamics of vehicle packets based on a macroscopic model on the basis of a Lagrangian ...
Jean-Patrick Lebacque, Tai-Yu Ma
core  

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

open access: yesAdvanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang   +7 more
wiley   +1 more source

Inter-technology Effects in Intelligent Transportation Systems [PDF]

open access: yes
This project examines the expected benefits of varying combinations of ITS applications: Freeway Service Patrol, Changeable Message Signs, and Ramp Metering.
David Gillen   +2 more
core  

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