Results 191 to 200 of about 13,370 (299)

Analyzing Mega-mobility Systems in Smart Cities: A Macro-Micro Integration with Feedback Paradigm Empowered by Artificial Intelligence. [PDF]

Research (Wash D C)
Wang Z, Cheng Q, Gu Z, Liu C, Cun D, Shi X, Wu X, Zhou Z, He X, Vlacic L, Liu Z.   +10 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Large-scale transportation governance: A tensorization-parallelization co-empowered framework. [PDF]

Innovation (Camb)
Gu Z, Kuang Y, Vu HL, Saberi M, Liu Y, Liu Z.   +5 more
europepmc   +1 more source

Microscopic Traffic Simulation of Automated Driving: Modeling and Evaluation of Traffic Performance.

The introduction of automated driving systems (ADSs) in road transportation systems will affect the traffic flow characteristics, and have ripple effects which will lead to larger societal implications. The traffic flow is characterized by speed, density, and vehicular throughput, which determine the road capacity and the traffic performance in terms ...
openaire   +4 more sources

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, EarlyView.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

Vibration Control and Micro-Forming Quality Guarantee of BMF-Based UHPC Wet Joints Under Traffic Loads Using Tuned Mass Dampers. [PDF]

Materials (Basel)
Wang Z, Zhang L, Zhou C, Wang P.
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

A principled basis for nonequilibrium network flows. [PDF]

Nat Commun
Yang YJ, Dill KA.
europepmc   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

Advanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu, Yulu Yang, Zhiqi Hao, Jing Xu, Huibo Zhao, Qiang Zhang, Deyong Ren, Xia Li, Guojun Dong, Lan Shen, Li Zhu, Jiang Hu, Zhenyu Gao, Qing Li, Qian Qian, Guangheng Zhang   +15 more
wiley   +1 more source

Universality in multispecies urban traffic. [PDF]

Commun Phys
Anagnostopoulos G, Geroliminis N.
europepmc   +1 more source