Results 51 to 60 of about 800,630 (271)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet [PDF]

Acta Cirúrgica Brasileira
Purpose: To evaluate, by quantitative and qualitative methods, the glomerular ultrastructure in Wistar rats fed a cafeteria diet. Methods: Male Wistar rats were divided into two groups at 21 days of age: control (C, n = 10) and cafeteria diet (CAF, n ...
Priscila Fernandes dos Santos, Diogo Benchimol de Souza, Eduardo José Lopes Torres, Waldemar Silva Costa, Francisco José Barcellos Sampaio, Bianca Martins Gregorio   +5 more
doaj   +1 more source

Cryogenic transmission electron microscopy nanostructural study of shed microparticles. [PDF]

PLoS ONE, 2013
Microparticles (MPs) are sub-micron membrane vesicles (100-1000 nm) shed from normal and pathologic cells due to stimulation or apoptosis. MPs can be found in the peripheral blood circulation of healthy individuals, whereas elevated concentrations are ...
Liron Issman, Benjamin Brenner, Yeshayahu Talmon, Anat Aharon   +3 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes

International Journal of Nanomedicine, 2014
Christopher B Fox,1 Sean K Mulligan,2 Joyce Sung,2 Quinton M Dowling,1 H W Millie Fung,1 Thomas S Vedvick,1 Rhea N Coler1 1Infectious Disease Research Institute, Seattle, WA, USA; 2NanoImaging Services, La Jolla, CA, USA Abstract: Development of lipid ...
Fox CB, Mulligan SK, Sung J, Dowling QM, Fung HWM, Vedvick TS, Coler RN   +6 more
doaj  

Single-crystal silver nanowires: Preparation and Surface-enhanced Raman Scattering (SERS) property

, 2011
Ordered Ag nanowire arrays with high aspect ratio and high density self-supporting Ag nanowire patterns were successfully prepared using potentiostatic electrodeposition within the confined nanochannels of a commercial porous anodic aluminium oxide (AAO)
alizadeh, Baoliang Sun, Chaney, Cheng, Drachev, Hu, Kim, Kong, Mardilovich, Moskovits, Mulvaney, Nikoobakht, Pan, Riveros, Shuxi Dai, Tian, Xiaohong Jiang, Yang, Yao, Zuliang Du   +19 more
core   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Interpretable and efficient contrast in scanning transmission electron microscopy with a diffraction grating beamsplitter

, 2018
Efficient imaging of biomolecules, 2D materials and electromagnetic fields depends on retrieval of the phase of transmitted electrons. We demonstrate a method to measure phase in a scanning transmission electron microscope using a nanofabricated ...
Chess, Jordan J., Ciston, Jim, Ercius, Peter, Feng, Wenchun, Harvey, Tyler R., Kotov, Nicholas A., McMorran, Benjamin J., Ophus, Colin, Pierce, Jordan S., Reis, Roberto M. S. dos, Yasin, Fehmi S., Özdöl, Vasfi Burak   +11 more
core   +1 more source

Is Small Perfect? Size Limit to Defect Formation in Pyramidal Pt Nanocontacts [PDF]

, 2007
We report high resolution transmission electron microscopy and ab initio calculation results for the defect formation in Pt nanocontacts (NCs). Our results show that there is a size limit to the existence of twins (extended structural defects).
D. S. Galvão, D. Ugarte, F. Sato, N. W. Ashcroft, R. M. Metzger, V. Rodrigues   +5 more
core   +3 more sources

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source