Results 41 to 50 of about 1,972,851 (282)
Post-acquisition image based compensation for thickness variation in microscopy section series
Serial section Microscopy is an established method for volumetric anatomy reconstruction. Section series imaged with Electron Microscopy are currently vital for the reconstruction of the synaptic connectivity of entire animal brains such as that of ...
Bogovic, John A. +2 more
core +1 more source
Polyamide-rubber blends: micrscopic studies of the deformation zone [PDF]
The morphology of injection moulded samples of polyamide—polybutadiene blends (85.15) with an average particle size of 0.3 μm was studied. The samples were fractured in a notched tensile test at crosshead speeds of 10−4 and 1 ms −1 and the structure of ...
Dijkstra, K. +4 more
core +4 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Assembly mechanism of the pleomorphic immature poxvirus scaffold
Immature poxviruses are characterized by nonicosahedral semiordered protein scaffolds critical for morphogenesis. Here, the authors use cryo-EM structures of Vaccinia virus D13 scaffold intermediates to explain their assembly mechanism.
Jaekyung Hyun +3 more
doaj +1 more source
Silver stain for electron microscopy [PDF]
Ammoniacal silver stain used for light microscopy was adapted advantageously for use with very thin biological sections required for electron microscopy.
Corbett, R. L.
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Cochleates derived from Vibrio cholerae O1 proteoliposomes : The impact of structure transformation on mucosal immunisation [PDF]
Cochleates are phospholipid-calcium precipitates derived from the interaction of anionic lipid vesicles with divalent cations. Proteoliposomes from bacteria may also be used as a source of negatively charged components, to induce calcium-cochleate ...
Adriana Callicó +10 more
core +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Noise2Atom: unsupervised denoising for scanning transmission electron microscopy images
We propose an effective deep learning model to denoise scanning transmission electron microscopy (STEM) image series, named Noise2Atom, to map images from a source domain S $\mathcal {S}$ to a target domain C $\mathcal {C}$ , where S $\mathcal {S}$ is ...
Feng Wang +3 more
doaj +1 more source
Background Next-generation sequencing (NGS) represents a significant advancement in clinical genetics. However, its use creates several technical, data interpretation and management challenges.
Maria Zanti +8 more
doaj +1 more source

