Results 81 to 90 of about 3,090,289 (293)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Phase transformation strengthening of high-temperature superalloys

Nature Communications, 2016
Nanoscale processes may directly impact macroscopic mechanical behaviour. Here authors describe a ‘phase-transformation strengthening’ mechanism in nickel-based high temperature alloys, allowing suppression of deleterious deformation processes at ...
T. M. Smith, B. D. Esser, N. Antolin, A. Carlsson, R. E. A. Williams, A. Wessman, T. Hanlon, H. L. Fraser, W. Windl, D. W. McComb, M. J. Mills   +10 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Electrostatic charging artefacts in Lorentz electron tomography of MFM tip stray fields [PDF]

, 2001
Using the technique of differential phase contrast (DPC) Lorentz electron microscopy, the magnetic stray field distribution from magnetic force microscopy (MFM) tips can be calculated in a plane in front of the tip using tomographic reconstruction ...
Scott, J., Ferrier, R.P., Gallagher, A., McVitie, S.   +3 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Electron Microscopy of “premelanin”

Journal of Investigative Dermatology, 1962
Masson's ammonia ted (reduced) silver nitrate technic (1) has been used in studies of the process of melanization. By this method Zimmermann and Becker (2) demonstrated the existence of premelanin in melanoblasts from 10 week old human fetuses. The term premelanin is defined, on the basis of the staining reaction using this method, as the substance of ...
Mishima, Yutaka, Loud, Alden V., Schaub, Frederick F.   +2 more
openaire   +2 more sources

Flagellar Motility and Structure in the Hyperthermoacidophilic Archaeon Sulfolobus solfataricus [PDF]

, 2007
Flagellation in archaea is widespread and is involved in swimming motility. Here, we demonstrate that the structural flagellin gene from the crenarchaeaon Sulfolobus solfataricus is highly expressed in stationary-phase-grown cells and under unfavorable ...
Szabó, Zalán,, Blum, Paul, Groeneveld, Maarten,, Sani, Musa,, Driessen, Arnold J. M., Albers, Sonja-Verena,, Zolghadr, Behnam, Zolghadr, Benham,, Albers, Sonja-Verena, Boekema, Egbert J.,, Albers, Sonja Verena, Groeneveld, Maarten, Blum, Paul,, Schelert, James, Sani, Musa, Szabo, Zalan, Zolghadr, Benham, Schelert, James,, Boekema, Egbert J., Driessen, Arnold J.M.,   +19 more
core   +2 more sources

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Incorrectly Focused Neodymium:Yttrium–Aluminum-Garnet (Nd:YAG) Laser Beam Leads to Massive Destructive Effects in Small-Aperture (Pinhole) Intraocular Lenses

Ophthalmology and Therapy
Introduction Pinhole intraocular lenses (IOLs) were developed to improve reading by compensating for loss of accommodative function. The IC-8® Apthera™ is a small-aperture presbyopia-correcting IOL that combines the proven principle of small-aperture ...
Andreas F. Borkenstein, Tatiana K. Kormilina, Harald Fitzek, Johannes Rattenberger, Gerald Kothleitner, Fabio E. Machado Charry, Eva-Maria Borkenstein   +6 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source