Results 181 to 190 of about 5,240,853 (330)

Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy

Science, 2008
Bo Huang, Wenqin Wang, M. Bates, X. Zhuang   +3 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A novel non-invasive imaging technique for mapping microplastic accumulation and distribution in different organ systems of Indian major carp <i>Labeo rohita</i> (Ham. 1822). [PDF]

Curr Res Toxicol
Siwach S, Singh A, Paul S, Gupta V, Gupta I, Negi RK.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Sub-microscopic schistosomiasis and soil-transmitted helminths in school children: molecular diagnostic evidence and implications for disease elimination. [PDF]

Sci Rep
Mac PA, Anderson KD, Dakul DA.
europepmc   +1 more source

Content-aware image restoration: pushing the limits of fluorescence microscopy

Nature Methods, 2018
Martin Weigert, Uwe Schmidt, Tobias Boothe, A. Müller, Alexandr Dibrov, Akanksha Jain, Benjamin Wilhelm, Deborah Schmidt, Coleman Broaddus, Siân Culley, M. Rocha-Martins, F. Segovia-Miranda, C. Norden, Ricardo Henriques, M. Zerial, M. Solimena, J. Rink, P. Tomančák, Loic A. Royer, Florian Jug, E. Myers   +20 more
semanticscholar   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

MicroLive: an image processing toolkit for quantifying live-cell single-molecule microscopy. [PDF]

Bioinform Adv
Aguilera LU, Raymond WS, Sears RM, Nowling NL, Munsky B, Zhao N.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Malaria misdiagnosis among febrile patients in Senegal: implications for the underestimation of Plasmodium species diversity and malaria burden. [PDF]

Malar J
Sambe BS, Diagne A, Diatta AS, Diaw SOM, Sarr I, Diatta HAM, Sané R, Guigma PYB, Senghor B, Diouf B, Sembene PM, Vigan-Womas I, Niang M.   +12 more
europepmc   +1 more source