Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Side-viewing axicon-integrated miniature fiber probe for extended depth of focus and ultrahigh lateral resolution endoscopic imaging. [PDF]
Liu Y +7 more
europepmc +1 more source
A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang +10 more
wiley +1 more source
Immunomodulatory Potential of a Composite Amniotic Membrane Hydrogel for Wound Healing: Effects on Macrophage Cytokine Secretion. [PDF]
Wang T, Zhu Z, Hua W, Xue S.
europepmc +1 more source
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti +4 more
wiley +1 more source
Synergistic Mechanism of Water-Alternating-Gas Injection and Elastic Microsphere Plugging for Gas Channeling Control in Immiscible Gas Flooding: Experimental Insights from the Weizhou 12-1 Oilfield. [PDF]
Zhang Y +5 more
europepmc +1 more source
Stamping Lithography on Arbitrary Surfaces based on Self‐Assembly of Colloidal Particles
A new method called Stamping Lithography for three‐dimensional (3D) circuits manufacturing is proposed, which comprises a resist mask stamping process based on self‐assembly of colloidal particles and a subsequent etching process. It replaces the photoresist with self‐assembled particles and the exposure process with stamping, making it feasible to ...
Guoxu Yu +8 more
wiley +1 more source
Advances of Drug-Loaded Microsphere Technology for Targeted Immunotherapy Against Prostate Cancer. [PDF]
Feng W.
europepmc +1 more source

