Results 31 to 40 of about 67,078 (267)

Preparation and In Vitro/Ex Vivo Evaluation of Buccoadhesive Discs of an Anti-Parkinson Drug: Relationship between Mucoadhesivity, Drug Release and Permeability [PDF]

Pharmaceutical Sciences, 2018
Background: Selegiline hydrochloride (Sel) is a drug applied for the therapy of early-step Parkinson's disease. In usual clinical doses, it is an elective irreversible MAO-B inhibitor.
Farnaz Monajjemzadeh, Mahsa Bagheri, Seyed Hassan Montazam, Mitra Jelvehgari   +3 more
doaj   +1 more source

In-fiber Silicon Microspheres [PDF]

Asia Communications and Photonics Conference 2015, 2015
We have proposed and demonstrated an approach to fabricate integrated in-fiber silicon microspheres, which have nearly atomically smooth surface roughness ~0.16 nm. The hybrid structure forms a cavity with high temperature sensitivity ~ 80 pm/°C.
Xiao, Limin, Healy, Noel, Webber, Zondy, Hawkins, Thomas, Jones, Maxwell, Ballato, John, Gibson, Ursula, Peacock, Anna   +7 more
openaire   +2 more sources

Refractometry of organosilica microspheres [PDF]

Applied Optics, 2007
9 pages, 8 ...
Seet, K. Y. T., Vogel, R., Nieminen, T. A., Knoner, G., Rubinsztein-Dunlop, H., Trau, M., Zvyagin, A. V.   +6 more
openaire   +5 more sources

Transfer functions of proteinoid microspheres

Biosystems, 2023
Proteinoids, or thermal proteins, are inorganic entities formed by heating amino acids to their melting point and commencing polymerisation to form polymeric chains. Typically, their diameters range from 10 to 100 micron. Some amino acids incorporated into proteinoid chains are more hydrophobic than others, leading proteinoids to cluster together when ...
Panagiotis Mougkogiannis, Neil Phillips, Andrew Adamatzky   +2 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Computed tomography and histopathological findings after embolization with inherently radiopaque 40μm-microspheres, standard 40μm-microspheres and iodized oil in a porcine liver model. [PDF]

PLoS ONE, 2018
PURPOSE:The present study compared standard computed tomography (CT) and histopathological findings after endovascular embolization using a prototype of inherently radiopaque 40μm-microspheres with both standard 40μm-microspheres and iodized oil in a ...
Dominik F Vollherbst, Theresa Gockner, Thuy Do, Kerstin Holzer, Carolin Mogler, Paul Flechsig, Alexander Harms, Christopher L Schlett, Philippe L Pereira, Götz M Richter, Hans U Kauczor, Christof M Sommer   +11 more
doaj   +1 more source

Stretching the Printability Metric in Direct‐Ink Writing with Highly Extensible Yield‐Stress Fluids

Advanced Functional Materials, EarlyView.
This study introduces “drawability” as a new metric for assessing printability in direct‐ink writing, focusing on gap‐spanning performance and speed robustness. By designing yield‐stress fluids with high extensibility, we demonstrate that extensional strain‐to‐break significantly enhances printability.
Chaimongkol Saengow, Samya Sen, Joaquin Yus, Eliza E. Lovrich, Amanda G. Hoika, Kelly M. Chang, Arielle A. Pfeil, Nellie Haug, Amy J. Wagoner Johnson, Randy H. Ewoldt   +9 more
wiley   +1 more source

pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution

Applied Sciences, 2021
Smart hollow polymeric microspheres have been widely applied in various fields such as controlled release, drug delivery, catalysis, and so on. Herein, a facile, green and one-step template-free method is introduced for preparing pH-responsive hollow ...
Chuhong Yu, Jing Peng, Jiuqiang Li, Maolin Zhai   +3 more
doaj   +1 more source

Machine Learning‐Assisted Inverse Design of Soft and Multifunctional Hybrid Liquid Metal Composites

Advanced Functional Materials, EarlyView.
A machine learning framework is presented for inverse design of synthesizable multifunctional composites containing both liquid metal and solid inclusions. By integrating physics‐based modeling, data‐driven prediction, and Bayesian optimization, the approach enables intelligent design of experiments to identify optimal compositions and realize these ...
Lijun Zhou, Yunsik Ohm, Ren‐Mian Chin, Olivia Kerr, Krithika Manohar, Mohammad H. Malakooti   +5 more
wiley   +1 more source