AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Ablation of CFRP Modified with Copper and Calcium Hydroxyapatites by Femtosecond Laser Pulses for Further Material Cutting and Milling Applications. [PDF]
Polymers (Basel)Šlevas P +6 more
europepmc +1 more source
Substrate Engineering of SWCNT p–n Junctions for Dual‐Mode Power Generation and Heat‐Flux Sensing
Advanced Science, EarlyView.Through substrate engineering alone, a single‐walled carbon nanotube p–n junction device switches between two functions under uniform infrared irradiation. A low‐absorbance substrate sustains a central hot junction for continuous power generation, whereas high‐absorbance substrates transiently invert the temperature gradient for sensitive heat‐flux ...
Ryota Tamai +3 more
wiley +1 more source
Theoretical Investigation of Early Cancer Biomarker Sensing Using a PMMA-Gold Hybrid Quasi-D-Shaped Photonic-Crystal-Fiber-Based Surface Plasmon Resonance Biosensor. [PDF]
Micromachines (Basel)Ramola A, Shakya AK, Balal N, Bergman A.
europepmc +1 more source
A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring
Advanced Science, EarlyView.This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali +7 more
wiley +1 more source
Polydimethylsiloxane in Optics. [PDF]
Polymers (Basel)Calixto S, Zitzumbo R, Alfaro-Gomez M.
europepmc +1 more source
Advanced Science, EarlyView.Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu +16 more
wiley +1 more source
Quantitative Analysis of Bisphenol A in Commercial Beverages. [PDF]
MoleculesFreitas AI, Ferreira MS, Marques JC.
europepmc +1 more source
Advanced Science, EarlyView.The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan +11 more
wiley +1 more source
Recent Progress in on-Demand Transfer-Enabled Integration of Wavelength-Scale Light Sources. [PDF]
NanophotonicsKim H +7 more
europepmc +1 more source