An analytical study of neocartilage from microtia and otoplasty surgical remnants: A possible application for BMP7 in microtia development and regeneration. [PDF]
PLoS ONE, 2020 To investigate auricular reconstruction by tissue engineering means, this study compared cartilage regenerated from human chondrocytes obtained from either microtia or normal (conchal) tissues discarded from otoplasties.
William J Landis +9 more
core +2 more sources
Objective quantitative methods to evaluate microtia reconstruction: A scoping review
JPRAS Open, 2023 Summary: Background: Commonly used methods to evaluate auricles are subjective and are therefore not specific, comprehensive, and precise nor effective in the assessment of microtia reconstruction outcomes.
Elsa M. Ronde +6 more
core +2 more sources
Evaluation of 4 Outcomes Measures in Microtia Treatment [PDF]
Plastic and Reconstructive Surgery, Global Open, 2017 BackgroundIn craniofacial microsomia, microtia and canal atresia pose formidable reconstructive challenges. We review our institutional experience in treating microtia and atresia to identify variables associated with 4 outcomes measures: complications ...
Emily Dubina +15 more
core +3 more sources
A simple ear splint for microtia patients
Indian Journal of Dental Research, 2015 Microtia is a congenital anomaly of the ear can occur as an isolated birth defect or as part of a spectrum of anomalies or as a syndrome. Microtia is often associated with impaired hearing and or total loss of hearing.
C J Venkata Krishnan +2 more
core +2 more sources
Understanding the molecular mechanisms of human microtia via a pig model of HOXA1 syndrome
Disease Models & Mechanisms, 2015 Microtia is a congenital malformation of the outer ears. Although both genetic and environmental components have been implicated in microtia, the genetic causes of this innate disorder are poorly understood.
Bo Pan +9 more
core +2 more sources
IL-6 signaling is required for the development and regeneration of ear cartilage in microtia. [PDF]
Front Cell Dev BiolIntroductionCongenital microtia is a birth defect characterized by auricular underdevelopment, with unclear pathogenesis and unidentified pathogenic genes.MethodsDifferential expression analysis, weighted co-expression network analysis (WGCNA), protein ...
Luan W +5 more
europepmc +2 more sources
Ten-year trends in the incidence of microtia: a nationwide population-based study from Taiwan
European Archives of Oto-Rhino-Laryngology, 2021 PURPOSE: Few studies have explored population-based incidence rates of microtia using nationwide data. The aim of this study was to analyze the 10-year secular trends in the incidence of microtia and/or anotia in Taiwan from 2008 to 2017 using nationwide
Yen-Fu Cheng +2 more
exaly +2 more sources
Microtia in the Netherlands: Clinical characteristics and associated anomalies
International Journal of Pediatric Otorhinolaryngology, 2014 Background: In Europe there have been few detailed reports on the clinical characteristics of microtia patient populations. The objective of the present study is to contribute to our insight of microtia in Europe by examining the Dutch microtia ...
Daan P F Van Nunen +2 more
exaly +2 more sources
PLoS ONE, 2014 Microtia is a congenital deformity where the external ear is underdeveloped. Genetic investigations have identified many susceptibility genes of microtia-related syndromes.
Yong-Biao Zhang (149201) +15 more
core +2 more sources
Anxiety, depression, and HRQoL in pediatric microtia patients following ear reconstruction: a cross-sectional study. [PDF]
Front PsychiatryObjectiveThe aim of this study was to evaluate the levels of anxiety, depression, and health-related quality of life (HRQoL) in patients with congenital microtia after ear recontruction surgery and identify influencing factors of HRQoL.MethodA cross ...
Liu X +9 more
europepmc +2 more sources