CRABP2 upregulation in perichondral stem cells is associated with microtia [PDF]
Microtia is a common congenital craniofacial malformation characterized by the partial or complete absence of the external ear structure. Despite its relatively high incidence, the pathogenesis of microtia remain poorly understood.
Jingheng Zhang +8 more
doaj +2 more sources
Microtia reconstruction is a challenging endeavor that has seen significant technique evolution. It is important to educate patients and their families to determine the best hearing rehabilitation and ear reconstructive options. Microtia is often associated with aural atresia, hearing loss, and craniofacial syndromes.
Randall Bly
exaly +4 more sources
IL-6 signaling is required for the development and regeneration of ear cartilage in microtia [PDF]
IntroductionCongenital microtia is a birth defect characterized by auricular underdevelopment, with unclear pathogenesis and unidentified pathogenic genes.MethodsDifferential expression analysis, weighted co-expression network analysis (WGCNA), protein ...
Wenkang Luan +5 more
doaj +2 more sources
Anxiety, depression, and HRQoL in pediatric microtia patients following ear reconstruction: a cross-sectional study [PDF]
ObjectiveThe aim of this study was to evaluate the levels of anxiety, depression, and health-related quality of life (HRQoL) in patients with congenital microtia after ear recontruction surgery and identify influencing factors of HRQoL.MethodA cross ...
Xinyi Liu +17 more
doaj +2 more sources
Patient and guardian perspectives on tissue engineering in microtia reconstruction. [PDF]
BackgroundTissue Engineering (TE) is a newer technology with ongoing development across various areas of healthcare. For microtia patients, TE holds promise as a viable option for ear reconstruction, making it essential to understand the perspectives of ...
Arya Sherafat +9 more
doaj +2 more sources
Prenatal Tympanic Ring Anomaly Without Microtia: A Subtle Clue Toward Severe Early-Onset Monogenic Disorders. [PDF]
ABSTRACT Objective To investigate the genetic etiologies and clinical significance of fetal tympanic ring abnormalities detected during second‐trimester ultrasound in the absence of microtia. Method Between November 2019 and June 2024, we examined the fetal tympanic rings of 10,277 unselected pregnant women during the 20–22 weeks of morphology ...
Lam YH +5 more
europepmc +2 more sources
Cat Eye Syndrome in a Sudanese Infant: Congenital Cataract in the Absence of Iris Coloboma: A Case Report. [PDF]
ABSTRACT We report the first Cat Eye Syndrome case from Sudan: a 5‐month‐old female with growth retardation, craniofacial dysmorphism, congenital cataract without iris coloboma, and ventricular septal defect. Cytogenetics confirmed 47,XX,+idic(22)(q11.2).
Khalid R, Fadl-Elmula I.
europepmc +2 more sources
The Importance of a Conchal Bowl Element in the Fabrication of a Three-Dimensional Framework in Total Auricular Reconstruction [PDF]
Background To construct a sophisticated three-dimensional framework, numerous modifications have been reported in the literature. However, most surgeons have paid little attention to the anatomical configuration of the concha and more to its deepness ...
Young Soo Kim
doaj +2 more sources
Background:. The temporoparietal fascia (TPF) flap has been successfully used in the treatment of microtia with primary or secondary cases. The literature contains numerous studies about its structure and vascular anatomy in adults.
Young Soo Kim, , MD, PhD
doaj +1 more source

