Results 181 to 190 of about 331,243 (309)

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Investigating Retinal Microvascular Changes Using OCT-Angiography: The Role of Oxidative Stress and Endothelial Dysfunction in Hypertensive Nephropathy. [PDF]

Medicina (Kaunas)
Malvasi M, Salomone L, Azzara I, Cammisotto V, Castellani V, Pignatelli P, Mitterhofer AP, Lai S, Tinti F, Loffredo L, Pacella E.   +10 more
europepmc   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source

Microvascular Free-Flap Outcomes at a Low-Volume Canadian Center: A Retrospective Analysis. [PDF]

Cureus
Kerr KD, Parrell TL, Hussey L, Angel D, Tibbo J.   +4 more
europepmc   +1 more source

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

Advanced Science, EarlyView.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang, Jintian Yu, Liang Yuan, Ziliang Fu, Yiming Yao, Lingna Chen, Shixiong Chen, Aikemu Ainiwaer, Xiaolin Cui   +8 more
wiley   +1 more source

Effect of COVID-19 on Retinal and Choroidal Microvasculature in the Pediatric Population: A Literature Review. [PDF]

Medicina (Kaunas)
Christou EE, Ashworth JL, Soliman NM, Kiraly P, Aslam T.   +4 more
europepmc   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

A Data-Efficient Computational Framework for Reconstruction and Simulation of Microcirculatory Perfusion. [PDF]

Microcirculation
Li P, Geng X, Shen Y, Yan M, Pan Q, Ning G.   +5 more
europepmc   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

A contrast-enhanced CMR-based risk score integrating microvascular obstruction and intramyocardial hemorrhage extent for prognostic evaluation. [PDF]

Insights Imaging
Gu XY, Yin TX, Yu LY, Zheng JY, Li ML, Zhou Y, Pu J, Xiang JY, Wu JP, Wu LM.   +9 more
europepmc   +1 more source