Results 31 to 40 of about 31,006 (261)

Insights to advance our management of myocardial ischemia: From obstructive epicardial disease to functional coronary alterations

open access: yesAmerican Heart Journal Plus, 2021
Study objective: The Coronary Vasomotor Disorders International Study Group (COVADIS) invited leading experts to address strategies to enhance our clinical understanding of INOCA with an emphasis on the management of coronary vasomotor disorders. Design:
C. Noel Bairey Merz   +13 more
doaj   +1 more source

Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]

open access: yes, 2013
<p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P.   +10 more
core   +1 more source

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve. [PDF]

open access: yes, 2015
AimsThe mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear.
Anderson, R David   +15 more
core   +1 more source

Vasomotor Dysfunction in Patients with Ischemia and Non-Obstructive Coronary Artery Disease: Current Diagnostic and Therapeutic Strategies

open access: yesBiomedicines, 2021
Many patients who present with symptoms or objective evidence of ischemia have no or non-physiologically-significant disease on invasive coronary angiography.
Amr Abouelnour, Tommaso Gori
doaj   +1 more source

Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments [PDF]

open access: yes, 2015
Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition.
Berry, Colin   +5 more
core   +1 more source

How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial

open access: yesInterventional Cardiology: Reviews, Research, Resources, 2019
Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge.
Thomas J Ford, Colin Berry
doaj   +1 more source

Exertional chest pain is sometimes more than just coronary atherosclerosis

open access: yesRevista Portuguesa de Cardiologia, 2021
Clinical case: A 64-year-old male, with cardiovascular risk factors and previous history of bilateral carpal tunnel syndrome, presented with exertional retrosternal pain. The resting echocardiogram was unremarkable.
G.J. Morgado   +8 more
doaj   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

open access: yes, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM   +15 more
core   +1 more source

Clinical features and outcomes of patients with stable or unstable chest pain and no-obstructive coronary artery disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundCoronary microvascular dysfunction can be responsible for both stable angina and acute coronary syndrome (ACS). There are scarce data, however, about comparisons of clinical characteristics and outcomes of these 2 groups of patients.Materials ...
Nello Cambise   +9 more
doaj   +1 more source

Systemic microvascular dysfunction in microvascular and vasospastic angina [PDF]

open access: yesEuropean Heart Journal, 2018
Coronary microvascular dysfunction and/or vasospasm are potential causes of ischaemia in patients with no obstructive coronary artery disease (INOCA). We tested the hypothesis that these patients also have functional abnormalities in peripheral small arteries.Patients were prospectively enrolled and categorised as having microvascular angina (MVA ...
Ford, Thomas J.   +18 more
openaire   +3 more sources

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