Results 191 to 200 of about 70,906 (304)

Intermittent hand and forearm immersion in 20°C water attenuates thermal, cardiovascular, and perceptual strain in older adults during heat stress

Experimental Physiology, EarlyView.
Abstract Adults >65 years of age experience deleterious health effects during extreme heat events at a greater rate than any other age cohort. The purpose of this study was to identify the effectiveness of acute intermittent hand and forearm (H+F) water immersion and/or chronic (7 week) folic acid supplementation on reducing thermal and cardiovascular ...
Rachel M. Cottle, Kat G. Fisher, Olivia K. Leach, David E. Conroy, Lacy M. Alexander, W. Larry Kenney   +5 more
wiley   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Interactive effect of retinal microvascular impairment and larger lesion diameter on cognitive impairment in lacunar infarction. [PDF]

Alzheimers Res Ther
Kwapong WR, Chen J, Chen Z, Zheng C, Guo Y, Liu Y, Cheng H, Qiu H, Luan X, Bonaventure IYM, Cheung CY, Wang Z.   +11 more
europepmc   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

Experimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen, Emily H. Reeve, Nick R. Winder, Grant D. Henson, Nayantara Arora, Thomas Leonhardt, Ainsley Hogan, Sahana Krishna Kumaran, Naly Setthavonsack, Victoria Krajbich, Art Riddle, Benjamin Zimmerman, Nabil J. Alkayed, Martin M. Pike, Randall L. Woltjer, Ashley E. Walker   +15 more
wiley   +1 more source

The Inter-Eye Differences of the Circumpapillary Microvasculature in Primary Open-Angle Glaucoma. [PDF]

Transl Vis Sci Technol
Sun JA, Johnson GE, Lee KM, Zhao Y, Saini C, Wang M, Chang AC, Aboobakar IF, Chung IY, Wiggs JL, Shen LQ.   +10 more
europepmc   +1 more source

The effect of repeated hot water immersion on microvascular function, glycaemic control and inflammation in White European and South Asian males

Experimental Physiology, EarlyView.
Abstract Individuals of South Asian (SA) descent display a higher risk for cardiovascular disease and type 2 diabetes mellitus than their White European (WE) counterparts. Heat therapy, such as hot water immersion (HWI), can improve microvascular function and glycaemic control, although effects across racial groups are unknown.
David Bellini, Alex Lloyd, Christof A. Leicht, Stephen J. Bailey, Lewis J. James, Matthew J. Maley   +5 more
wiley   +1 more source

Lecanemab alters basement membrane collagen IV in viable microvessels isolated from brains with high Alzheimer's disease neuropathology. [PDF]

J Alzheimers Dis
Damodarasamy M, Hernandez GJ, Johnson RS, Keene CD, Latimer CS, MacCoss MJ, Banks WA, Erickson MA, Reed MJ.   +8 more
europepmc   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Friend of GATA2 Variant Ser657Gly Is Associated With Coronary Microvascular Disease. [PDF]

Circ Genom Precis Med
Guerraty MA, Verma SS, Ko YA, McQuillan MA, Conlon DM, Tobias JW, Levin MG, Haury W, Zheng F, Cherlin T, Zhang C, Zhang C, Judy R, Tishkoff SA, Damrauer SM, Arany Z, Rader DJ.   +16 more
europepmc   +1 more source

Quantifying microvascular responses to local heating using optical coherence tomography: Comparison between skin sites and sex differences

Experimental Physiology, EarlyView.
Summary of the study design, metholodgy, results and conclusions. Abstract Due to a lack of technical capacity to directly visualise and quantify microvessels in the skin, little is known regarding regional and/or sex differences. We compared diameter, velocity, flow and density at four regional sites using a novel optical coherence tomography (OCT ...
Juliene G. Costa, Kristanti W. Wigati, Louise H. Naylor, Helen Jones, Robert A. McLaughlin, Daniel J. Green   +5 more
wiley   +1 more source