Results 61 to 70 of about 29,720 (220)

STAT3 decoy decreases microvessel density in vivo by acting directly on the endothelial cells.

, 2014
Ploy-L-lactic acid scaffolds were seeded with HUVECs and then implanted on the flank of nude athymic mice. The mice were the treated with either the STAT3 decoy oligonucleotide or the STAT3 mutant control via peri-scaffold injection for 15 days.
Seungwon Kim (505757), Jennifer R. Grandis (505756), Jeffrey N. Myers (222748), Jonah D. Klein (505754), Daisuke Sano (222747), Malabika Sen (505755)   +5 more
core   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Survivin expression, HPV positivity and microvessel density in oropharyngeal carcinomas and relationship with survival time

, 2016
Introduction: Among head and neck cancers, those of the oral cavity and oropharynx are the second most prevalent following the larynx. This study aimed to research immunohistochemical expression of survivin, HPV positivity and microvessel density in ...
Süt, Necdet, Tastekin, Ebru, Fulya Oz Puyan, Turkkan, Gorkem, Can, Nuray, Nilufer Kilic Durankus, Durankus, Nilufer Kilic, Ebru Tastekin, Caloglu, Vuslat Yurut, Puyan, Fulya Oz, Gorkem Turkkan, Necdet Sut, Murat Caloglu, Vuslat Yurut Caloglu, Nuray Can   +14 more
core   +1 more source

Retinal Vessel Segmentation: A Comprehensive Review From Classical Methods to Deep Learning Advances (1982–2025)

Advanced Intelligent Systems, EarlyView.
Four decades of retinal vessel segmentation research (1982–2025) are synthesized, spanning classical image processing, machine learning, and deep learning paradigms. A meta‐analysis of 428 studies establishes a unified taxonomy and highlights performance trends, generalization capabilities, and clinical relevance.
Avinash Bansal, Jan Kubíček, Jana Bahrová, Alice Varyšová, Martin Augustýnek, Marek Penhaker, Juraj Timkovič   +6 more
wiley   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting β-catenin Signaling to Induce Expression of VEGFA

EBioMedicine, 2017
We previously reported that overexpression of DHX32 contributes to the growth and metastasis of colorectal cancer (CRC). However, the underlying mechanism is not largely characterized. Herein, we reported that DHX32 in CRC cells upregulated expression of
Huayue Lin, Zanxi Fang, Yuanhui Su, Peihua Li, Jingkun Wang, Hongfeng Liao, Qing Hu, Chunlei Ye, Yizhen Fang, Qing Luo, Zhiyuan Lin, Chao Pan, Fen Wang, Zhong-Ying Zhang   +13 more
doaj   +1 more source

Relationship of vascular endothelial growth factor expression and microvessel density with clinicopathological features of triple-negative breast cancer

Zhongguo linchuang yanjiu
"Objective To detect the expression of vascular endothelial growth factor (VEGF) and microvessel density in cancer tissues of breast cancer patients, and to analyze their relationship with clinicopathological characteristics of breast cancer.
ZHAO Benxin>, WANG Fei, LIU Pei, HAN Rongbo
doaj   +1 more source

Microvessel density is significantly decreased in the remote myocardium eight weeks post MI.

, 2013
A to D, Representative tissue slide from remote myocardium with vWF staining in sham (A), one week (B), four weeks (C) and eight weeks group (D); E, Accumulated results show microvessel density is significantly increased in peri-infarct zone after MI. No
Wen Lu (153883), Lin Ling (296367), Biao Xu (221284), Rong Gu (231159), Bin Zong (343954), Qin Dai (177488), Jun Xie (53987)   +6 more
core   +1 more source

Maspin and c-erbB-2 expression in correlation with microvessel density in invasive ductal breast cancer

Folia Histochemica et Cytobiologica, 2011
Maspin is a unique member of the serpin family involved in regulation of cell migration, apoptosis and angiogenesis in breast and prostate cancers. In this study maspin expression in comparison with c-erbB-2 (HER2/neu) oncogene expression and microvessel
Izabela Berdowska, Izabela Kasprzyk, Mirosław Sopel   +2 more
doaj   +1 more source

Intra-tumoural microvessel density in human solid tumours

, 2002
Over the last decade assessment of angiogenesis has emerged as a potentially useful biological prognostic and predictive factor in human solid tumours.
R Byers, Byers, R.; id_orcid, Hasan, J., Jayson, Gordon C.; id_orcid, J Hasan, G C Jayson   +5 more
core   +1 more source