Results 171 to 180 of about 532,678 (300)

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Microwave Ablation for the Treatment of Non-Colorectal Cancer Liver Metastasis. [PDF]

Cancers (Basel)
Lanari J, Lazzari S, Billato I, Naldini C, De Nardi C, Tamponi G, Volpato D, Furlanetto A, D'Amico FE, Vitale A, Gringeri E, Cillo U.   +11 more
europepmc   +1 more source

Interfacial Salinity–Transport Matching in 3D Solar Evaporators: A Framework for Brine‐Stable Solar Interfacial Evaporation

Advanced Science, EarlyView.
A transport‐matching framework is developed to evaluate brine‐stable 3D solar evaporators beyond evaporation rate alone. Using PVA/GNP porous evaporators as a model system, the study shows that stable brine evaporation requires balanced heat generation, liquid replenishment, salt redistribution, and vapor removal rather than maximum dry temperature or ...
Mohammad Sajad Sorayani Bafqi, Arun Prakash Aranga Raju, Omid Doustdar, Reza Nekouie Esfahani, Ali Sadaghiani   +4 more
wiley   +1 more source

Trans-Arterial Chemoembolization Combined with Microwave Ablation versus Microwave Ablation Alone for 3-5 cm Hepatocellular Carcinoma: A Multicenter Retrospective Study. [PDF]

J Hepatocell Carcinoma
Han D, Li F, Wang G, Niu Y, Wang J, Liang C, Li H, Ju S, Li K, Wang X, Li Y, Niu C, Duan X.   +12 more
europepmc   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Mechanical bowel displacement to enable safe microwave ablation of a peripheral hepatic tumor in Chilaiditi anatomy. [PDF]

Radiol Case Rep
Liljedahl S, Morcos D, Kitley C.
europepmc   +1 more source

Dual‐Functional Terahertz Manipulation of EuBa2Cu3O7 Superconductors via Cooper Pair Dynamics

Advanced Science, EarlyView.
We use a spintronic‐metasurface THz emitter to realize chiral THz generation. Using polarization‐tunable THz pulses, we investigate equilibrium and photoinduced THz responses in a 43 nm thick EuBa2Cu3O7 (EBCO) thin film. The EBCO film achieves 46.81 dB EMI shielding and 113% photoinduced THz modulation with 19.0 ps recovery, enabled by Cooper‐pair ...
Zhangshun Li, Meng Yang, Zuanming Jin, Junxue Li, Zhiqiang Lan, Chen Huang, Alexei V. Balakin, Alexander P. Shkurinov, Yan Peng, Yiming Zhu, Songlin Zhuang   +10 more
wiley   +1 more source

Percutaneous Cryoablation Versus Microwave Ablation for Hepatocellular Carcinoma: Comparative Study of Safety and Oncologic Outcomes. [PDF]

Radiol Imaging Cancer
Chlorogiannis DD, Bhagavatula SK, Silverman SG, Dabiri BE, Tuncali K, Levesque VM, Gottumukkala RV, Lan Z, Shyn PB.   +8 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source