Results 51 to 60 of about 21,062 (300)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

3D Quantitative Ablation Margins for Prediction of Ablation Site Recurrence After Stereotactic Image-Guided Microwave Ablation of Colorectal Liver Metastases:A Multicenter Study [PDF]

, 2021
Background: Three-dimensional (3D) volumetric ablation margin assessment after thermal ablation of liver tumors using software has been described, but its predictive value on treatment efficacy when accounting for other factors known to correlate ...
Candinas, Daniel, de Jong, Koert P, Weber, Stefan, Tinguely, Pascale, Ruiter, Simeon J S; id_orcid, Ruiter, Simeon J S, Freedman, Jacob, Paolucci, Iwan, de Haas, Robbert J, Engstrand, Jennie   +9 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Heat Transfer Study in Breast Tumor Phantom during Microwave Ablation: Modeling and Experimental Results for Three Different Antennas

, 2020
It is worldwide known that the most common type of cancer among women is breast cancer. Traditional procedures involve surgery, chemotherapy and radiation therapy; however, these treatments are invasive and have serious side effects.
Arturo Vera Hernández, Citlalli Jessica Trujillo-Romero, Lorenzo Leija, Mario Francisco Jesús Cepeda-Rubio, Rocío Ortega-Palacios   +4 more
core   +1 more source

A Compact Spin‐Coated Graphene UWB Antenna for Breast Tumor Detection

Advanced Engineering Materials, EarlyView.
A compact, spin‐coated graphene ultra‐wideband patch antenna designed for breast tumor detection, capable of distinguishing between malignant and benign tumors. This innovative antenna can serve as an effective initial screening tool, particularly in resource‐limited settings such as rural areas, where access to advanced medical equipment like MRI and ...
Raja Rashidul Hasan, Shuvra Saha, Sumit Hassan Eshan, Rinku Basak, Md. Nahian Al Subri Ivan, Ahmed Murtuza Saleque, Raja Tariqul Hasan Tusher, Sadia Zabin, Md. Abdur Rahman, Yuen Hong Tsang   +9 more
wiley   +1 more source

Safety and feasibility of bronchoscopic microwave ablation technology for peripheral lung cancer: a multi-center, prospective, single-arm study protocol

BMC Surgery
Background Microwave ablation is a well-established therapeutic option for percutaneous treatment of lung tumors, however transbronchial microwave ablation remains under investigation.
Jason Beattie, Ray Parrish, Laith Ayasa, Paula Aranguren, Francisco L. Uribe-Buritica, Mariana Nino Lopez, Cristiana M. Pineda, George Cheng, Michal Senitko, Ramsy Abdelghani, Anil Magge, Camilo A. Avendano, Fayez Kheir, Kai Swenson, Mihir Parikh, Jennifer Wilson, Paul A. VanderLaan, Sidhu Gangadharan, Adnan Majid   +18 more
doaj   +1 more source

Powder Optimization Strategies for Binder Jetting Printing of BaTiO3 and Ba0,6Sr0,4TiO3 Ceramics

Advanced Engineering Materials, EarlyView.
Powder optimization is investigated to enable binder jetting of BaTiO3 and Ba0.6Sr0.4TiO3 ferroelectric ceramics. The antagonistic relationship between flowability and binder compatibility is addressed through binder impregnation of granulated powders and fumed silica addition to fine powders.
Fanny Pruvost, Lionel Presmanes, Soléna Colin, Marie Vidal, Sophie Guillemet‐Fritsch   +4 more
wiley   +1 more source

Safety and efficacy of microwave ablation for abdominal wall endometriosis: A retrospective study

Frontiers in Surgery, 2023
ObjectivesThis retrospective study aimed to evaluate the safety and feasibility of ultrasound-guided microwave ablation in the treatment of abdominal wall endometriosis (AWE).BackgroundAWE is a rare form of endometriosis that often results in cyclic ...
Yujiang Liu, Wanwan Wen, Linxue Qian, Ruifang Xu   +3 more
doaj   +1 more source

Percutaneous stereotactic image-guided microwave ablation for malignant liver lesions. [PDF]

, 2019
Thermal ablation has proven beneficial for hepatocellular carcinoma and possibly for colorectal liver metastases, but data is lacking for other liver metastases. Computer-assisted navigation can increase ablation efficacy and broaden its indications.
Perrodin, Stéphanie, Kim-Fuchs, Corina, Candinas, Daniel, Banz, Vanessa, Lachenmayer, Anja, Maurer, Martin   +5 more
core   +1 more source