Results 71 to 80 of about 75,845 (309)

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Trace Metal Contents of NIST 1634c and NIST 8505 Multi-Element Petroleum Reference Materials: Compilation of Published Data and New Results Evaluating Acid Digestion Procedures

Geosciences
Knowledge of the trace element contents of petroleum can improve crude oil exploration and refining and aid environmental studies. Analytical challenges prompt experimentation with various digestion methods and analytical techniques, but the assessment ...
Emiliya Raeva, Lora Bidzhova, Gatien Morin, Svetoslav Georgiev   +3 more
doaj   +1 more source

Microwave-assisted hydrothermal carbonization of rapeseed husk: A strategy for improving its solid fuel properties [PDF]

, 2016
Hydrothermal carbonization of a waste biomass material is a green and promising technique for improving its solid fuel properties, which does not require pretreatment procedure such as drying of the biomass.
Elaigwu, Sunday E., Greenway, Gillian M.
core   +2 more sources

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

THE DEVELOPMENT OF ANALYTICAL METHODS FOR THE ELEMENTAL DETERMINATION OF BIOTIC INDICATORS PRESENT IN AQUATIC ECOSYSTEMS

Studia Universitatis Babes-Bolyai Chemia, 2017
In our research, we investigate the accumulation extent of the inorganic contaminants accessing the aquatic food chain, including zooplankton and fish species through model experiments.
Petra HERMAN, Sándor HARANGI, Milán FEHÉR, István FÁBIÁN, Edina BARANYAI   +4 more
doaj   +1 more source

Gold determination in soil by ICP-MS: comparison of sample pretreatment methods

Journal of Analytical Science and Technology, 2020
At present, the direct gold determination in geological samples by inductively coupled plasma mass spectrometry (ICP-MS) is still an arduous challenge due to both spectral and background interferences.
Xiaodan Tang, Bing Li, Jilong Lu, Hongyan Liu, Yuyan Zhao   +4 more
doaj   +1 more source

Digestão de óleo lubrificante encapsulado em forno de microondas com radiação focalizada por adição de amostra ao reagente pré-aquecido. [PDF]

, 2014
FOCUSED-MICROWAVE-ASSISTED DIGESTION OF ENCAPSULATED LUBRICATING OILS: GRADUAL SAMPLEADDITION TO PRE-HEATED ACID. The applicability of the recently proposed procedure based on gradual sample addition tomicrowave-assisted pre-heated concentrated acid is ...
BRESSANI, F. A., COSTA, L. M., NOGUEIRA, A. R. de A., NÓBREGA, J. A., SILVA, H. O.   +4 more
core  

Assessing depleted uranium (DU) contamination of soil, plants and earthworms at UK weapons testing sites [PDF]

, 2007
Depleted uranium (DU) weapons testing programmes have been conducted at two locations within the UK. An investigation was therefore carried out to assess the extent of any environmental contamination arising from these test programmes using both alpha ...
Angus B. MacKenzie, Bem, Boag, Bou-Rabee, Danesi, Danesi, Desideri, Di Lella, Di Lella, Ellam, Fisenne, Goldstein, Hamilton, Hu, Ian W. Oliver, Jia, Jia, John G. Farmer, Langdon, Magnoni, Margaret C. Graham, Robert M. Ellam, Rodriguez, Sansone, Sheppard, Sheppard, Tanaka, Trueman, Vera Tome, Yafa, Yamamoto, Yoshida   +31 more
core   +2 more sources

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Determination of Trace Selenium in Biological Samples by Inductively Coupled Plasma-Mass Spectrometry with Microwave Digestion

Yankuang ceshi, 2014
Hydride Generation-Atomic Fluorescence Spectrometry (HG-AFS) with wet digestion is classical method to determine the trace element selenium in biological samples.
FENG Yong-ming, XING Ying-xiang, LIU Hong-qing, ZHANG Yong   +3 more
doaj   +2 more sources