Results 71 to 80 of about 656,890 (291)

Use of factorial design for optimization of microwave-assisted digestion of lubricating oil [PDF]

open access: yes, 2005
This work proposes the use of factorial design for optimization of microwave-assisted digestion of lubricating oil. The accuracy of digestion procedures is affected by critical experimental parameters, such as sample amount, concentrated acid volumes ...
Nóbrega,Joaquim A.   +7 more
core   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

open access: yesAdvanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang   +6 more
wiley   +1 more source

Effects of microwave radiation on the digestion of proteins involved in body fluid identification [PDF]

open access: yes, 2020
Body fluid identification plays an important role in understanding how the events during a crime may have taken place. The presence of a body fluid may help identify an individual who committed a crime, while the type of body fluid present may help ...
Fox, Aaron J
core   +1 more source

Gold determination in soil by ICP-MS: comparison of sample pretreatment methods

open access: yesJournal of Analytical Science and Technology, 2020
At present, the direct gold determination in geological samples by inductively coupled plasma mass spectrometry (ICP-MS) is still an arduous challenge due to both spectral and background interferences.
Xiaodan Tang   +4 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

open access: yesAdvanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi   +16 more
wiley   +1 more source

Chemical Oxygen Demand (cod) Using Microwave Digestion

open access: yes, 2015
A new approach to determine the Chemical Oxygen Demand (COD) using a microwave digestion to replace the conventional time consuming reflux method is proposed.
Rohwedder J.J.R., Jardim W.F.
core   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

open access: yesAdvanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu   +6 more
wiley   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

open access: yesAdvanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang   +12 more
wiley   +1 more source

Microwave digestion method according to [30] (modified) with quartz inlay in microwave beakers allows a separation of sample chemicals, which minimizes Se losses and contamination and enhances efficiency.

open access: yes, 2018
Microwave digestion method according to [30] (modified) with quartz inlay in microwave beakers allows a separation of sample chemicals, which minimizes Se losses and contamination and enhances efficiency.
Monika Stelling (4915660)   +4 more
core   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

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