Results 71 to 80 of about 43,065 (264)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

New driving parameters for diamond deposition reactors: pulsed mode versus continuous mode

Materials Research, 2003
Experimental investigation and modeling of pulsed H2/CH4 plasmas used for diamond deposition are presented. Two plasma configurations are studied : a 2.45 GHz microwave cavity configuration and a 915 MHz surface-wave configuration.
Alix Gicquel, Khaled Hassouni, Guillaume Lombardi, Xavier Duten, Antoine Rousseau   +4 more
doaj   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Green reverse water gas shift reaction achieved by microwave-induced plasma

Green Chemistry Letters and Reviews
The reverse water-gas shift (RWGS) reaction is a promising route to produce syngas that is a valuable precursor for synthetic fuel production. However, this reaction is possible only using catalysts.
Balazs Peter Kiss, Zsolt Dobo, George Kaptay   +2 more
doaj   +1 more source

Lattice Distortion‐Driven Metal Exsolution in Perovskite Oxides

Advanced Science, EarlyView.
This study elucidates the mechanism of lattice distortion‐driven exsolution through a combination of computational simulations and experimental approaches. Lattice distortion facilitates the formation of oxygen vacancies and subsequent metal segregation, thereby enhancing the exsolution behavior.
Yo Han Kim, Uchan Jeon, Hyeongwon Jeong, Bo‐Ram Won, Jeong Woo Han, Jae‐ha Myung   +5 more
wiley   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Control of plasma profile in microwave discharges via inverse-problem approach

AIP Advances, 2013
In the manufacturing process of semiconductors, plasma processing is an essential technology, and the plasma used in the process is required to be of high density, low temperature, large diameter, and high uniformity.
Yasuyoshi Yasaka, Naoki Tobita, Akihiro Tsuji   +2 more
doaj   +1 more source

Field‐Frustrated Cooperative Distortions: Suppressing Jahn‐Teller Ordering via Microwave Annealing

Advanced Science, EarlyView.
Microwave annealing decouples local Jahn‐Teller distortions from long‐range cooperative ordering in CuFe2O4, stabilizing a metastable cubic phase that remains locally distorted yet globally symmetry‐frustrated. Synchrotron XRD, PDF, XPS, and in situ thermal cycling reveal how non‐equilibrium MW‐phonon interactions suppress cooperative orbital‐lattice ...
Daryoosh Vashaee, Kelvin Dsouza
wiley   +1 more source

Electrolyte Design for Simultaneous Interfacial Stabilization in Si||NCM811 Full Cells

Advanced Science, EarlyView.
A dual‐additive electrolyte (DAEL) system was optimized to regulate interfacial reactions in both Si anode and the NCM811 cathode. DAEL suppresses gas evolution and degradation, enabling stable interphases. These synergistic effects enhance electrochemical stability and extend battery cycle life in high‐energy lithium‐ion cells.
Seo Yun Jang, Kyu Hong Lee, Juhyoung Kim, Dong Wook Kim, Kyu Hyoung Lee, Do Youb Kim, Se‐Hee Kim   +6 more
wiley   +1 more source