Results 231 to 240 of about 133,902 (294)

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Engineered TIGIT‐Blockade Membrane Vesicles Synergize with Microwave Ablation to Mediate Liver Metastases Eradication

Advanced Science, EarlyView.
Microwave ablation (MWA) represents a highly effective and clinically significant therapeutic modality for the treatment of liver metastases. This study develops engineered cell membrane vesicles to specifically target the transition zone of MWA for liver metastases. This strategy can inhibit VEGF‐mediated immunosuppression, block CD155/TIGIT signaling
Shaoyue Li, Weichen Xu, Yuting Shen, Xuexia Shan, Jiawei Sun, Shisi Ding, Xiaodong Hou, Shaoning Zhang, Zhiyuan Niu, Taixia Wang, Xin Guan, Xiao Li, Weiwei Ren, Dou Du, Huixiong Xu, Wenwen Yue, Liping Sun   +16 more
wiley   +1 more source

Microwave technologies for biomedical diagnosis and therapy: advances, challenges, and perspectives. [PDF]

Mikrochim Acta
Montoya-Villada S, Reyes-Vera E, Orozco J.   +2 more
europepmc   +1 more source

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Microwave Photonic Sensors

Journal of Lightwave Technology, 2021
Microwave photonics is a field that studies the interaction between microwave and optical waves for the generation, transmission, processing, and measurements of microwave signals by means of photonics, to take advantage of the high speed and broad bandwidth offered by modern photonics.
openaire   +1 more source

Microwave imaging sensors

2020
Microwave imaging (MWI) systems are nowadays acquiring an ever-growing importance in numerous application fields, such as non-destructive testing (NDT) in civil and industrial applications, subsurface sensing and ground penetrating radar (GPR) prospection, through-wall imaging (TWI) for security and biomedical imaging.
Fedeli, Alessandro, Pastorino, Matteo, Randazzo, Andrea   +2 more
openaire   +1 more source

Microwave‐based sensors

Microwave and Optical Technology Letters, 2015
ABSTRACTA microwave‐based sensor for detection of cracks is proposed. Two types of resonators are designed and analyzed. The first resonator is a ring resonator with stubs attached to the rings. It resonates at a frequency of 2.3 GHz with an insertion loss of −38.51 dB and a return loss of −3.25 dB.
Rebecca Abraham, K. Usha Kiran
openaire   +1 more source

Microwave vehicle sensor

37th IEEE Vehicular Technology Conference, 1987
A microwave vehicle sensor is described. It is based on microwave radiometry, that is measurement of microwave energy (or temperature) emitted or reflected by bodies. This technique allows detection of passing vehicules as well as measurement of speed and length. Abnormal road surface condition is also detected.
R. Garceau, C.T. Le Dinh, M. Loloyan, G. Terreault   +3 more
openaire   +1 more source