Results 231 to 240 of about 152,722 (386)

Trending@RWU Law: Professor Emily Sack\u27s Post: More Death Penalty Puzzles Highlighted by New Supreme Court Case [PDF]

, 2015
Sack, Emily
core   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam

, 2016
José Francisco Nunes Pereira das Neves, Mariana Moraes Pereira das Neves Araújo, Fernando de Paiva Araújo, Clarice Martins Ferreira, Fabiana Baeta Neves Duarte, Fábio Heleno de Lima Pace, Laura Cotta Ornellas, Todd H. Baron   +7 more
openalex   +1 more source

Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital*

Pediatric Critical Care Medicine, 2016
R. Tasker, H. Goodkin, Iván Sánchez Fernández, K. Chapman, N. Abend, R. Arya, J. Brenton, J. Carpenter, W. Gaillard, T. Glauser, Joshua L. Goldstein, A. Helseth, M. Jackson, K. Kapur, M. Mikati, K. Peariso, M. Wainwright, A. Wilfong, Korwyn L Williams, T. Loddenkemper   +19 more
semanticscholar   +1 more source

Impact of Obesity and MASH on Zonal Hepatocellular Statin Exposure: Pharmacodynamic Insights From a Permeability‐Limited Multicompartment Liver Model

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Obesity, MASH and Statins: Insights from a PBPK/PD Zonal Liver Model. ABSTRACT Statins are frequently prescribed for hyperlipidemia, a common comorbidity in patients with obesity and/or metabolic dysfunction‐associated steatohepatitis (MASH). However, limited knowledge exists on how MASH may alter statin disposition within hepatocytes where the statin ...
William A. Murphy, Noora Sjöstedt, Mailys De Sousa Mendes, Mattie Hartauer, Kim L. R. Brouwer, Sibylle Neuhoff   +5 more
wiley   +1 more source

Impact of sequential administration of detomidine, butorphanol, and midazolam on sedation, ataxia, stimulus response, and bispectral index in horses. [PDF]

Front Vet Sci
Thorn CA, Wilson DV, Wang S, Horne WA.
europepmc   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Efficacy and Safety of Remimazolam versus Dexmedetomidine and Midazolam in Awake Endotracheal Intubation for Difficult Airway Patients: A Randomized Controlled Study. [PDF]

Drug Des Devel Ther
Tang L, Zhang M, Guo J, Zhang M, Chen W, Zhao X, Huang J, Sheng L.   +7 more
europepmc   +1 more source

Remifentanil/midazolam versus fentanyl/midazolam for analgesia and sedation of mechanically ventilated neonates and young infants: a randomized controlled trial [PDF]

, 2012
Lars Welzing, André Oberthuer, Shino Junghaenel, Urs Harnischmacher, H. Stützer, Bernhard Roth   +5 more
openalex   +1 more source

Quantum Inspired Universal Analog Computation Based on Circuits

Advanced Quantum Technologies, EarlyView.
We propose an analog scheme of classical circuit for universal quantum computation. The information is encoded using correlated electrical signals, and the number of the basic computing components employed in our circuit design is consistent with the number of the quantum gate in the quantum circuit.
Hanxu Zhang, Yifan Sun, Xiangdong Zhang
wiley   +1 more source