Robert S. Lopez. The Commercial Revolution of the Middle Ages, 950–1350. New York: Cambridge University Press. 1976. Pp. xi, 180. Cloth $9.95, paper $3.95 [PDF]
David Nicholas
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Association between frailty and chronic lung diseases in middle aged and older population. [PDF]
Zhou D +10 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Detection of Decrease in Stereognostic Ability of the Tongue in the Middle-Agers
K Shigenori, Wataru Masuda, K Yoshino
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Frailty and Socioeconomic Development in the European Region-Associations with Mortality in Middle-Aged and Older Adults. [PDF]
O'Caoimh R, Wall A, O'Donovan MR.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Explaining middle-aged women's experiences of reproductive health care of the middle-aged program (30-59 years old) during the covid-19 epidemic. [PDF]
Noroozi M +2 more
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The role of socio-economic and lifestyle factors in hearing function in middle-aged adults. [PDF]
Sharp I +4 more
europepmc +1 more source

