Results 61 to 70 of about 1,932,630 (281)

Determinants of short-period heart rate variability in the general population [PDF]

, 2001
Decreased heart rate variability (HRV) is associated with a worse prognosis in a variety of diseases and disorders. We evaluated the determinants of short-period HRV in a random sample of 149 middle-aged men and 137 women from the general population ...
Bolte, H.-D., Eckardstein, A. von, Hense, H. W., Kark, J. D., Kuch, Bernhard, Sapoznikov, D., Sinnreich, R.   +6 more
core   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

A Cosmic Ray Positron Anisotropy due to Two Middle-Aged, Nearby Pulsars?

, 2008
Geminga and B0656+14 are the closest pulsars with characteristic ages in the ran ge of 100 kyr to 1 Myr. They both have spindown powers of the order 3e34 erg/s at present.
Barwick, Berezinskii, Boezio, Buesching, C. Venter, Caraveo, de Jager, DuVernois, Ginzburg, I. Büsching, M. S. Potgieter, Manchester, Mao, O. C. de Jager, Potgieter, Rees, Sefako, Venter   +17 more
core   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

Signatures of middle aged, nearby pulsars in the cosmic ray lepton spectrum?

, 2011
Recent data reported by the PAMELA and ATIC experiments, as well as cosmic ray lepton results from FERMI and H.E.S.S. collaborations sparked a series of papers explaining these results either by contributions of electron positron pairs to the local ...
Büsching, Ingo, deJager, Okker C.
core   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

Optical-uv spectrum and proper motion of the middle-aged pulsar b1055-52

, 2010
PSRB1055-52 is a middle-aged (~535 kyr) radio, X-ray, and gamma-ray pulsar showing X-ray thermal emission from the neutron star (NS) surface. A candidate optical counterpart to PSRB1055-52 was proposed by Mignani and coworkers based on Hubble Space ...
Abdo, Apellánez, Becker, Bignami, Brinkmann, Brisken, Caraveo, Caraveo, Cordes, De Luca, de Zeeuw, G. G. Pavlov, Greiveldinger, Guillemot, Høg, Kaplan, Kargaltsev, Kargaltsev, Lasker, Lattanzi, Manchester, Manchester, Mignani, Mignani, Monet, Newton, Nota, O. Kargaltsev, Pavlov, Pavlov, Pavlov, Pavlov, Perryman, Predehl, R. P. Mignani, Roeser, Seaton, Shibanov, Skrutskie, Thompson, Vande Putte, Vaughan, Wang, Zacharias, Zacharias, Zavlin   +45 more
core   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Weight change and 15 year mortality: results from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study. [PDF]

, 2018
Studies have reported a higher mortality risk associated with weight loss, particularly in middle-aged and older adults, although some of these studies did find that gaining weight was also associated with an increased mortality risk. We examined changes

core   +2 more sources