Results 51 to 60 of about 2,054,147 (357)

Mechanical versus Bioprosthetic Aortic Valve Replacement in Middle-Aged Adults: A Systematic Review and Meta-Analysis

open access: yesJournal of Cardiovascular Development and Disease, 2023
Background: Mechanical prostheses and bioprosthetic prostheses have their own advantages and disadvantages. Mechanical ones are recommended for younger patients (70 years old). There is still debate regarding which kind of prosthesis is better for middle-
Yefan Jiang   +4 more
doaj   +1 more source

Gamma rays from molecular clouds illuminated by cosmic rays escaping from interacting supernova remnants

open access: yes, 2010
Recently, gamma-ray telescopes AGILE and Fermi observed several middle-aged supernova remnants (SNRs) interacting with molecular clouds. It is likely that their gamma rays arise from the decay of neutral pions produced by the inelastic collision between ...
Abdo   +53 more
core   +1 more source

Antidepressants and age [PDF]

open access: yes, 2011
Antidepressants as a commodity have been remarkably little-studied by economists. This study shows in new data for 27 European countries that 8% of people (and 10% of those middle-aged) take antidepressants each year.
Blanchflower, David G.   +1 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Acute Responses of Cardiac Biomarkers to Intermittent and Continuous Exercise Are Related to Age Difference but Not I/D Polymorphism in the ACE Gene

open access: yesFrontiers in Physiology, 2020
PurposeThe purpose of this study was to determine the (i) cardiac biomarker (cTnI and NT-proBNP) responses to moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) in the middle-aged and young groups, (ii) relationship
Akram Falahati   +2 more
doaj   +1 more source

Is home-based, high-intensity interval training cycling feasible and safe for patients with knee osteoarthritis? Study protocol for a randomized pilot study [PDF]

open access: yes, 2017
Background: Osteoarthritis (OA) is a degenerative joint disease affecting the knee joint of many middle-aged and older adults. As OA symptoms typically involve knee pain and stiffness, individuals with knee OA are often insufficiently physically active ...
Grigg, Josephine   +2 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Are Japanese Women Less Physically Active Than Men? Findings From the DOSANCO Health Study

open access: yesJournal of Epidemiology, 2021
Background: Previous research has established that women accumulate less moderate-to-vigorous physical activity (MVPA) than men. To date, however, little is known about the gender differences in device-based activity patterns of sedentary behavior (SB ...
Shiho Amagasa   +12 more
doaj   +1 more source

Benefits and Risks of Weight-Loss Treatment for Older, Obese Women [PDF]

open access: yes, 2013
Background: A key issue in the treatment of obesity in older adults is whether the health benefits of weight loss outweigh the potential risks with respect to musculoskeletal injury.
Daniels, Michael J.   +4 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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