Results 81 to 90 of about 1,932,630 (281)

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]

open access: yes, 2019
Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy   +4 more
core   +1 more source

Prevalence and risk factors of hypertension for the middle-aged population in China — results from the China Health and Retirement Longitudinal Study (CHARLS)

open access: yesClinical and Experimental Hypertension, 2019
Background: The prevalence of hypertension in middle-aged people is increasing. However, few studies have examined the risk factors of hypertension among the middle-aged population.
Zhen Li, Chang Fu, Fan Yang, Zongfu Mao
doaj   +1 more source

XMM observations of three middle-aged pulsars

open access: yes, 2003
X-ray observations of middle-aged pulsars allow one to study nonthermal radiation from pulsar magnetospheres and thermal radiation from neutron star (NS) surfaces.
Pavlov, G. G, Zavlin, V. E.
core  

Influence of Body Composition on Arterial Stiffness in Middle-Aged Adults: Healthy UAL Cross-Sectional Study [PDF]

open access: yes, 2019
Background and objectives: Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly
Alcaraz Ibáñez, Manuel   +4 more
core   +1 more source

Ejecta detection in the middle-aged Galactic supernova remnant G296.1-0.5 observed with Suzaku

open access: yes, 2011
In this paper, we report the detection of ejecta in the middle-aged Galactic supernova remnant G296.1-0.5 with the X-ray Imaging Spectrometer onboard the Suzaku satellite. The spectra of three lobes, north, southeast and southwest and inter-lobe regions,
A. Sezer   +29 more
core   +1 more source

Glial βii spectrin contributes to paranode formation and maintenance [PDF]

open access: yes, 2018
Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D.   +12 more
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Comparing the Quality of Life and the Ability to Perform Daily Activities in Elderly and Middle-Aged Monocular Veterans

open access: yesطب جانباز, 2019
Aims: Aging is an inevitable part of human life, which is associated with reduced ability, increased dependence, and susceptibility to a variety of diseases.
Minooiefar J.   +4 more
doaj  

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