Results 91 to 100 of about 430,476 (264)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Wars of the Middle Ages

open access: yesУправленческое консультирование, 2018
The article discusses the role of war in the life of medieval society. Particular attention is paid to the human dimension of war. The author notes the characteristics of war in the Middle Ages. The article highlighted the distinctive features of the war
Vladimir Kuzmich Karnaukh
doaj  

“A Mirror for Men” – Reconstructing a Medieval Polishing Bench and Putting it to the Test

open access: yesEXARC Journal, 2020
In the late 5th century AD, the famous Ostrogoth Theoderic the Great received a truly regal gift from the king of the Warini: he was given highly elaborated swords, richly decorated and able to cut through armour.
Florian Messner
doaj  

A pan-European art trade in the late middle ages: Isotopic evidence on the master of Rimini enigma. [PDF]

open access: yesPLoS One, 2022
Kloppmann W   +5 more
europepmc   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

L’épineuse lecture du « trône de Dagobert » : analyses techniques, stylistiques et matérielles

open access: yesArchéologie Médiévale
The “throne of Dagobert” is one of the most famous pieces of medieval furniture in Western Europe. Discovered in the first half of the 12th c. by Suger, abbot of Saint-Denis, it was linked to the last great Merovingian king Dagobert. However, its precise
Cécile Lagane, Lise Saussus
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Home - About - Disclaimer - Privacy