Results 71 to 80 of about 430,476 (264)

Food globalization in southern Central Asia: archaeobotany at Bukhara between antiquity and the Middle Ages. [PDF]

open access: yesArchaeol Anthropol Sci, 2023
Mir-Makhamad B   +4 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Bruno da Longobucco (da Longoburgo): The first academic surgeon in the Middle Ages. [PDF]

open access: yesFront Surg, 2022
Pata F   +5 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Il medioevo citato di Giovanni Pascoli. Re Enzo fra storia e simbolo [PDF]

open access: yesParole Rubate, 2019
This essay examines Giovanni Pascoli’s Canzoni di Re Enzio within the nineteenth-century context of medieval revival. Far from stylizations and adaptations, the philological precision of the evocation of historical facts is linked to the tragedy of human
Francesca Irene Sensini
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correction to: The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]

open access: yesAesthetic Plast Surg, 2023
Marinozzi S   +6 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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