Results 1 to 10 of about 12,195,030 (401)

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice [PDF]

eLife, 2016
The FDA approved drug rapamycin increases lifespan in rodents and delays age-related dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action in the context of healthy ...
Anderson, Anisimov, Atarashi, Augustine, Bates, Blackwell, Chen, Dai, de Oliveira, Ericsson, Ericsson, Flynn, Goldman, Halloran, Hard, Harrison, Hothorn, Johnson, Johnson, Johnson, Kaeberlein, Lamming, Majumder, Mannick, Mathew, Miller, Miller, Paulson, Prakash, Ramos, Treuting, Wilkinson, Xu, Zhang   +33 more
core   +2 more sources

"I feel too lethargic to do physical activity": Perceptions of Iranian adults on the barriers to perform regular physical activity [PDF]

Health Promotion Perspectives, 2021
Background: Despite the intention to perform physical activity (PA), a number of individuals cannot manage to have PA program on a regular basis. In this study we explored the barriers of regular PA behavior among healthy adults in Tabriz, Iran. Methods:
Behrouz Fathi, Haidar Nadrian, Mina Hashemiparast, Saeed Nikookheslat, Safooreh Esmaeilzadeh, Rahim Khodayari-Zarnaq   +5 more
doaj   +1 more source

Measuring Online Health Information Seeking Skills and its Related Factors in a Middle-Aged Population [PDF]

Preventive Care in Nursing and Midwifery Journal, 2022
Background: Internet is an important source of online health information seeking. Middle-aged people, may face more health-threatening challenges if they lack seeking skills.
Fatemeh Sadat Izadi- Avanji, Mahboobeh Kafaei -Atrian, Jalal Hashemi-Demneh   +2 more
doaj   +1 more source

Earth’s middle age [PDF]

Geology, 2014
This research was funded through Natural Environment Research Council (grant NE/J021822/1) and the APC was paid through the RCUK OA block grant.
Cawood, Peter Anthony, Hawkesworth, Chris   +1 more
openaire   +3 more sources

Steps per Day and All-Cause Mortality in Middle-aged Adults in the Coronary Artery Risk Development in Young Adults Study

JAMA Network Open, 2021
Key Points Question Are step volume or intensity associated with premature mortality among middle-aged Black and White women and men? Findings In this cohort study of 2110 adults with a mean follow-up of 10.8 years, participants taking at least 7000 ...
Amanda E. Paluch, K. Gabriel, J. Fulton, C. Lewis, P. Schreiner, B. Sternfeld, S. Sidney, J. Siddique, K. Whitaker, M. Carnethon   +9 more
semanticscholar   +1 more source

Frailty trajectory among community-dwelling middle-aged and older adults in Korea: evidence from the Korean Longitudinal Study of Aging

BMC Geriatrics, 2022
Background There is no study on the frailty trajectory including both middle-aged and older people, and the understanding of the long-term frailty trajectory is insufficient.
Ah Ram Jang, Hae Sagong, Ju Young Yoon
doaj   +1 more source

Effect of tubular heater structures on the thermal behaviors of waxy crude oil

Case Studies in Thermal Engineering, 2023
In this paper, we research the temperature field, flow field and melting law of gelled crude oil with different diameters, locations and inclination angles of heating tube by numerical simulation method.
Hang Dong, Nan Guo, Lianjie Zhang, Jian Zhao   +3 more
doaj   +1 more source

Perspectives on healthy aging in middle age: Evidence for health promotion interventions

Journal of Education and Health Promotion, 2022
CONTEXT: Understanding how middle-aged people perceive healthy aging and what they need to do to stay healthy as they age can help public policy planning to enhance the lifestyles of middle-aged and elderly people.
Mahnaz Solhi, Razieh Pirouzeh, Nasibeh Zanjari   +2 more
doaj   +1 more source

The association between HDL‐C and stroke in the middle‐aged and elderly: A cross‐sectional study

Brain and Behavior, 2023
Background Previous epidemiological studies have indicated that high‐density lipoprotein cholesterol (HDL‐C) is inversely associated with the risk of cardiovascular disease. However, this issue has aroused controversy in recent years.
Yang Hu, Min Song, Dongmei Wu, Yuqing Zhang, Gongbo Li, Haiyan Luo   +5 more
doaj   +1 more source

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice [PDF]

, 2013
We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2-/NO3- data from "middle-aged" (6-8 months old) C57BL/
A Torres, AA Beharka, AK Schroder, C Franceschi, C Franceschi, C Nathan, CC Chow, CE Lagoa, CR Gomez, DC Morrison, DE Zak, Derek Barclay, Derya Unutmaz, DO Adams, E Alvarez, E Cevenini, EZ Bagci, EZ Bagci, F Aujard, F L’Episcopo, FM Ocasio, G Nieman, H Ochi, H Saito, H Wang, IR Turnbull, J Plowden, JM Cavaillon, JM Prince, John Bartels, K Tateda, KM Greeneltch, L Alvarez-Rodriguez, L Ferrucci, M Gurven, MA West, MJ Yang, R Kumar, R Ostan, RA Kohman, Rami A. Namas, RB Effros, RJ Fahy, RL Zhang, Rosemary Hoffman, Ruben Zamora, S Daun, S Gordon, SC Kang, SF Bradley, SN Zykova, T Inamizu, Timothy R. Billiar, TP Plackett, U Fagiolo, W Schumer, W Wiktor-Jedrzejczak, Y Hasegawa, Y Ito, Y Vodovotz, Y Vodovotz, Y Vodovotz, Yoram Vodovotz, Z Yang   +63 more
core   +10 more sources