Results 141 to 150 of about 2,629,220 (336)
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Objective This paper summarized the experience in treating middle⁃aged and elderly patients with brain trauma⁃induced coagulopathy (BTIC). Methods and Results From January 2015 to May 2019, 3 BTIC patients (50-85 years old) were diagnosed by clinical ...
Zhu⁃feng GAO +5 more
doaj
On the Occurrence of Retinal Hemorrhage after Middle Age, and Its Bearing on the Duration of Life [PDF]
, 1897 Hasket Derby
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
ABCS Health SciencesIntroduction: The ageing process is associated with a higher prevalence of depression and cognitive impairment, negatively affecting health. Objective: Analyse the effects of cognitive impairment and depressive symptoms on the risk of functional ...
Milla Bitencourt Cabral +5 more
doaj +1 more source
An Introduction to the Economic History of England: The Middle Ages. [PDF]
, 1915 J. H. Clapham, E. Lipson
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Caught in the Middle? Occupancy in Multiple Roles and Help to Parents in a National Probability Sample of Canadian Adults [PDF]
This paper considers for a Canadian national probability sample of middle-aged women and men the question of how typical is the experience of being "caught in the middle" between being the adult child of elderly parents and other roles.
Anne Martin-Matthews +2 more
core
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
The Palace of Minos, a Comparative Account of the Successive Stages of the Early Cretan Civilization as Illustrated by the Discoveries at Knossos. Volume I: The Neolithic and Early and Middle Minoan Ages. By Sir Arthur Evans [PDF]
, 1922 Edith Hall Dohan
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source