Results 141 to 150 of about 10,494,190 (367)

Sewing as Authority in the Middle Ages  [PDF]

open access: yesZeitschrift für Medien- und Kulturforschung, 2015
Dieser Essay betrachtet mittelalterliches Nähen im Licht von Austins Sprechakttheorie. Indem er Manuskripte, Reliquien, Ablässe und sogar die Mitra eines Bischofs analysiert, argumentiert der Artikel, dass Nähen eine Weise war, den rituellen Gebrauch der Objekte einzusetzen oder zu intensivieren – ob es sich nun um zeremonielle, devotionale, oder ...
openaire   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Dataset of youth and middle-aged unemployment in households in Kwara State, Nigeria

open access: yesData in Brief
This article shares the findings from survey conducted between November 2021 and April 2022 across the three senatorial districts of Kwara state, Nigeria.
Adebayo Mohammed Ojuolape   +2 more
doaj  

Which Generation Shows the Most Prudent Data Sharing Behaviour? [PDF]

open access: yesarXiv, 2018
We report from a study performed in ten European countries, where we asked about attitudes and behaviour towards data sharing behaviour. We looked into the differences between members of age groups. We find that there are more similarities than differences between the age groups, with the exception of young people more often tending to use fake ...
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Effect of tubular heater structures on the thermal behaviors of waxy crude oil

open access: yesCase Studies in Thermal Engineering, 2023
In this paper, we research the temperature field, flow field and melting law of gelled crude oil with different diameters, locations and inclination angles of heating tube by numerical simulation method.
Hang Dong   +3 more
doaj  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy