Results 141 to 150 of about 11,148,453 (358)

Association of physical fitness and motor ability at young age with locomotive syndrome risk in middle-aged and older men: J-Fit+ Study [PDF]

, 2020
Shaoshuai Shen, Koya Suzuki, Yoshimitsu Kohmura, Noriyuki Fuku, Yuki Someya, Hisashi Naıto   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Градът Карвуна? (Извори и археология)

Приноси към българската археология, 2018
This study reviews all available sources and publications about the territory known in the 11th–14th century under the name of the Karvuna land (Karvunskata zemya), Karvona chora, Karvuna archontate and the town of Karvuna.
Valentin Pletnyov
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial

, 2013
Martin de Bock, José G. B. Derraik, Christine Brennan, Janene B. Biggs, Philip E. Morgan, Steven C. Hodgkinson, Paul L. Hofman, Wayne S. Cutfield   +7 more
openalex   +2 more sources

Association between soluble α-klotho and mortality risk in middle-aged and older adults [PDF]

, 2023
Min‐Hsiang Chuang, Hung‐Wei Wang, Yun‐Ting Huang, Ming‐Yan Jiang   +3 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Presenting Medieval Gambling and Pub Life

EXARC Journal, 2012
There are many legendary games in the Middle Ages with professed losses of clothes, horses and, what is more, whole estates, and even halves of kingdoms. But was money really the most important part of gambling?
Zsuzsanna Sőregi
doaj  

REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles of the eNOS/NO/cGMP pathway and supplementation with L-arginine

, 2017
Jiaye Jiang, Zhongyuan Gan, Yuan Li, Wenqi Zhao, Hanqing Li, Jian‐Pu Zheng, Yan Ke   +6 more
openalex   +2 more sources

Desertion of farms around Oslo in the late middle ages [PDF]

, 1962
Andreas F. Holmsen
openalex   +1 more source