Results 181 to 190 of about 10,907,811 (379)

1. The Absolute Dynastic State

open access: yes, 1958
One of the most significant developments of the early modern period was the evolution of the national state from its beginnings in the feudal monarchy of the High and Late Middle Ages.
Bloom, Robert L.   +6 more
core  

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Africa’s Transitions to the Middle Ages

open access: yesMedieval Worlds, 2022
Paolo Tedesco
doaj   +1 more source

Author Correction: Spotted phenotypes in horses lost attractiveness in the Middle Ages. [PDF]

open access: yesSci Rep, 2020
Wutke S   +16 more
europepmc   +1 more source

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