Results 91 to 100 of about 467,597 (305)

Exploring climatic variability and drought characteristics in Morocco’s Sais Plateau and Middle Atlas: A statistical and spectral analysis [PDF]

BIO Web of Conferences
Extreme climate change phenomena are a global reality with major repercussions on hydrosystems. Drought is particularly concerning in the southern Mediterranean region, threatening water availability and related behavior. Morocco, located in North Africa
Qadem Zohair, Ettaqy Abderrahim
doaj   +1 more source

Performance of a First-Level Muon Trigger with High Momentum Resolution Based on the ATLAS MDT Chambers for HL-LHC

, 2015
Highly selective first-level triggers are essential to exploit the full physics potential of the ATLAS experiment at High-Luminosity LHC (HL-LHC).
Gadow, P., Kortner, O., Kortner, S., Kroha, H., Müller, F., Richter, R.   +5 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Petrascula iberica (DRAGASTAN & TRAPPE), Tersella genotii BARATTOLO & BIGOZZI, and the relationships of club-shaped dasycladalean algae during Late Triassic-Early Jurassic times

Geologia Croatica, 2008
New observations on abundant material from the type locality of Petrascula iberica (DRAGASTAN & TRAPPE) GRANIER et al. 2003, reveal the presence of a reproductive structure (ampulla) located on the inner-middle part of each primary lateral. This fact
Filippo Barattolo, Bruno Granier, Roberta Romano, Bruno Ferré   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

AN UNUSUAL CASE OF UNILATERAL ATLANTO-OCCIPITAL ASSIMILATION WITH SKULL ASYMMETRY

National Journal of Medical Research, 2012
A congenital fusion of the atlas to the base of occiput is defined as assimilation of Atlas. This condition is due to failure in segmentation and separation of the most caudal occipital sclerotome and first cervical sclerotome during the first week of ...
Sangeeta J Rajani, Ila M Suttarwala, Rajani Jitendra   +2 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Taxonomic and Ecological Interaction of Leishmaniasis Vectors (Diptera: Psychodidae) in Sefrou Province (Middle Atlas Morocco). [PDF]

ScientificWorldJournal, 2022
Talbi FZ, Taam A, El Omari H, Hilali S, Fadil M, El Khayyat F, Najy M, Mrani Alaoui M, El-Akhal F, Alami A, Amaiach R, Lahouiti K, Taroq A, El Ouali Lalami A.   +13 more
europepmc   +1 more source