Results 81 to 90 of about 471,464 (304)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Ammonoids of the Middle Devonian family Maenioceratidae in the Anti-Atlas of Morocco

European Journal of Taxonomy
The ammonoids of the family Maenioceratidae from Givetian sedimentary rocks of the Anti-Atlas (Morocco) are investigated. The study is based on new collections stored in the Museum für Naturkunde, Berlin.
Jürgen Bockwinkel, Dieter Korn
doaj   +1 more source

Heat Flow Density in a region with Hot Springs- NW of Portugal and SW of Galicia (Spain) [PDF]

, 2019
Heat flow density and temperature are studied in a region characterized by a very marked topography and the existence of thermal springs. The work was made with results obtained in studies involving heat sources in the region due to the decay of ...
Duque, Maria Rosa
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Lithosphere structures dynamics in the central High Atlas (Morocco) by seismic tomography and gravimetric data

Geodesy and Geodynamics, 2019
We investigate sedimentological and tectonic processes at the central High Atlas, in order to understand their functioning and to build a geodynamic model that placed the area in its current geological frame.
Y. Timoulali, M. Bouiflane, G. Bouskri, R. Azguet, Y. El Fellah   +4 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Crustal thickness beneath Atlas region from gravity, topographic, sediment and seismic data

Geodesy and Geodynamics, 2020
The Atlas region in northwest Africa is characterized by the Quaternary volcanism and elevated topography with past complex tectonic mitigation between the African and European plates.
Franck Eitel Kemgang Ghomsi, Robert Tenzer, Sévérin Nguiya, Animesh Mandal, Robert Nouayou   +4 more
doaj   +1 more source

Late Cenozoic tectonics of the Middle Atlas Mountains, Morocco: Continental deformation in the diffuse western Mediterranean plate boundary

, 1999
Copyright 1999, Francisco Gomez. See also: http://atlas.geo.cornell.edu/dissertations/Gomez_1999.htmThe Atlas Mountains of North Africa, located in the African foreland of the Alpine mountain belts, comprise a 2,000 km long Cenozoic mountain chain ...
Gomez, Francisco
core  

Sedimentary provenance of siliciclastic rocks from the Lalla Mouchaa Calcschists Formation (Coastal Block, Western Rehamna): Evidence of denudation of ca. 2 Ga basement in the Moroccan Meseta. [PDF]

, 2018
Paleoproterozoic basement rocks (ca. 2Ga) are scarce along the European and North African Paleozoic mountain chains (Fig.1a). In Morocco, ca. 2.2-2Ga granitic rocks (Gasquet et al., 2008; Kouyaté et al., 2013) have been exclusively reported in the ...
El Attari, A., El Houicha, M., Ennih, N., Ezzouhairi, H., Fekkak, A., Gama, C., Jouhari, A., Pereira, M.F., Silva J.B.   +8 more
core  

Evidence for surface uplift of the Atlas Mountains and the surrounding peripheral plateaux: Combining apatite fission-track results and geomorphic indicators in the Western Moroccan Meseta (coastal Variscan Paleozoic basement) [PDF]

, 2010
This work represents an initial attempt to link the evolution of the topography in relation to the general tectonic framework of western Morocco. For this purpose, in a section of the Western Moroccan Meseta different tools are combined in order to ...
A. Azdimousa, A. Jabaloy, Ait Brahim, Ayarza, Babault, Barbero, Bargach, Baudin, Braun, Braun, British Oceanographic Data Centre, Burov, Chèvromont, D. Gómez-Ortiz, Davison, El Hadi, Fullea, Fullea-Urchulutegui, Ghorbal, Guiraud, Harmand, Hoepffner, Hurford, Hurtrez, J. Estupiñán, J.V. Pérez-Peña, Johansson, Ketcham, Ketcham, L. Asebriy, L. Barbero, Lifton, M. Vázquez, M.J. Rodríguez-Peces, Mahmood, Masek, Michard, Michard, Michard, Missenard, Mrini, O'Callaghan, Ohmori, Price, Pérez-Peña, Pérez-Peña, R. Tejero, Rayner, Reiners, Schumm, Strahler, Tahiri, Tarboton, Tassi, Teixell, Teixell, Teixell, Tejero, Zeyen   +58 more
core   +2 more sources