Results 161 to 170 of about 467,597 (305)

Manganese mineralization in the northern Middle Atlas (Aderj mining zone, Morocco): Petro-structural and geochemical analysis. [PDF]

Heliyon
Laiche M, Hinaje S, Drissi Y, Yaagoub D, El Fartati M, Ouahzizi Y, Laksir A.   +6 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Authentication of Ziziphus lotus Honey from the Middle Atlas Mountains of Morocco: Physicochemical Properties, Mineral Content, Sugar, Polyphenol Profiles, and Antioxidant Capacity. [PDF]

ACS Omega
Bouddine T, Kachmar MR, Akdad M, Bouymajane A, Ajebli M, Mothana RA, Alanzi AR, Hajjaj H, Khallouki F, Reybroeck W, Van Poucke C, Hajji L.   +11 more
europepmc   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

A comparative analysis of dendrometric, macromorphological, and micromorphological characteristics of Pistacia atlantica subsp. atlantica and Pistacia terebinthus in the middle Atlas region of Morocco. [PDF]

Open Life Sci
Bassouya M, Chedadi M, Zahra JF, Kara M, Assouguem A, Ullah R, Ibrahim MA, Bari A, Fidan H, Soufyane L, Alami A, Bari A.   +11 more
europepmc   +1 more source

Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects

Advanced Science, EarlyView.
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su, Jian Qin, Hui Shen, Ling‐Li Zeng, Baojuan Li, Jin Liu, Xuemei Song, Li Liu, Weidan Pu, Tongjian Bai, Huaning Wang, Hong Yin, Kai Wang, Lingjiang Li, Dewen Hu   +14 more
wiley   +1 more source

Diversity and Population Sizes of Wintering Waterbirds in the Wetlands of the Saïss-Middle Atlas Region (North-Central Morocco): Main Survival Factors and Evaluation of Habitat Loss. [PDF]

Animals (Basel)
Squalli W, Mansouri I, Douini I, Achiban H, Saghrouchni H, El Agy A, Fadil F, Wink M, Dakki M.   +8 more
europepmc   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Effects of Different Solvents on the Total Phenol Content, Total Flavonoid Content, Antioxidant, and Antifungal Activities of Micromeria graeca L. from Middle Atlas of Morocco. [PDF]

Biochem Res Int
El Kamari F, El Omari H, El-Mouhdi K, Chlouchi A, Harmouzi A, Lhilali I, El Amrani J, Zahouani C, Hajji Z, Ousaaid D.   +9 more
europepmc   +1 more source

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source