Results 191 to 200 of about 121,974 (243)

Clipping first policy for middle cerebral artery aneurysm: A single-center cohort study. [PDF]

open access: yesSurg Neurol Int
Dokponou YCH   +7 more
europepmc   +1 more source

Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung ischemia/reperfusion injury (LIRI) is a primary contributor to morbidity and mortality following lung transplantation. Dexmedetomidine (DEX) protects the lungs from I/R injury, but the underlying mechanisms remain uncertain. This paper examined the protective effect of DEX in LIRI and elucidated the potential regulation involved. LIRI was
Chun‐Huan Hu   +4 more
wiley   +1 more source

Simultaneous Photoacoustic and Laser‐Induced Ultrasound Imaging of Animals and Humans via a Semi‐Transparent Ultrasound Transducer

open access: yesLaser &Photonics Reviews, EarlyView.
Combined photoacoustic (PA) and ultrasound (US) imaging commonly requires an external pulser to transmit US waves, making systems relatively complicated and suboptimal. Here simultaneous PA and laser‐induced US imaging is demonstrated without using a US pulser. A semi‐transparent ultrasound transducer converts some portion of excitation laser energy to
Bjarne Perleberg   +8 more
wiley   +1 more source

Prevalence and Clinical Characteristics of the LRRK2 p.L1795F Variant in Central Europeans with Early‐Onset and Familial Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) p.L1795F variant was proposed as a genetic risk factor for Parkinson's disease (PD). However, its prevalence, phenotype, and origin remain unknown. Objective The aim was to evaluate the frequency and phenotype of p.L1795F in early‐onset PD (EOPD) and familial PD compared to healthy controls (HC ...
Miriam Ostrozovicova   +35 more
wiley   +1 more source

Diffusion along Perivascular Spaces as a Marker for Glymphatic System Impairment in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background The aim was to investigate if glymphatic function is impaired in patients with Huntington's disease (HD) and its clinical relevance. Methods Forty‐nine subjects carrying mutant Huntingtin (mHTT), comprising 35 manifest (mHD) and 14 pre‐manifest (PreHD), and 35 healthy controls (HC) were recruited in this study.
Jin‐Hui Yin   +3 more
wiley   +1 more source

AI-Driven Information for Relatives of Patients with Malignant Middle Cerebral Artery Infarction: A Preliminary Validation Study Using GPT-4o. [PDF]

open access: yesBrain Sci
Al Barajraji M   +7 more
europepmc   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

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