Results 11 to 20 of about 59,331 (203)

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
wiley   +1 more source

Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register [PDF]

, 2017
Purpose: Beyond intravenous thrombolysis, evidence is lacking on acute treatment of minor stroke caused by large artery occlusion. To identify candidates for additional endovascular therapy, we aimed to determine the frequency of non-haemorrhagic ...
Ahmed, Niaz, Bar, Michal, Cooray, Charith, Ford, Gary A., Frol, Senta, Lees, Kennedy R., Mazya, Michael V., Moreira, Tiago, Sekaran, Lakshmanan, Toni, Danilo, Wahlgren, Nils, Švigelj, Viktor   +11 more
core   +1 more source

Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

Ibrain, EarlyView., 2023
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen, Xia Zhang, Hai‐Qing Zhang, Zhong Luo, Xue‐Jiao Zhou, Tao Liang, Fei Yang, Jun Zhang, Zu‐Cai Xu   +8 more
wiley   +1 more source

Specific neuroprotective effects of manual stimulation of real acupoints versus non-acupoints in rats after middle cerebral artery occlusion [PDF]

, 2013
The objective of this study was to investigate the effectiveness and specific effects of acupuncture on ischemic-induced damage in rats after permanent middle cerebral artery occlusion. Cerebral ischemia was induced by middle cerebral artery occlusion in
Fan, NX, Li, XL, Luo, D, Meng, HZ, Shi, MX, Zhang, NY   +5 more
core   +2 more sources

Protein kinase C inhibition attenuates vascular ET(B )receptor upregulation and decreases brain damage after cerebral ischemia in rat [PDF]

, 2007
BACKGROUND: Protein kinase C (PKC) is known to be involved in the pathophysiology of experimental cerebral ischemia. We have previously shown that after transient middle cerebral artery occlusion, there is an upregulation of endothelin receptors in the ...
DK Ways, E Stenman, E Stenman, ED Högestätt, Emelie Stenman, H Hara, H Memezawa, H Memezawa, J Aronowski, J Chuquet, J Hansen-Schwartz, JB Bederson, JL Knopf, K Naruse, L Coussens, Lars Edvinsson, M Henriksson, M Henriksson, M Henriksson, M Henriksson, MA McAuley, Marie Henriksson, MJ Mulvany, N Bowling, NJ Lodge, Petter Vikman, R Bright, S Koponen, S Miettinen, S Savithiry, SA Menzies, SS Beg, T Engelhorn, T Masaki, TR Patel, TR Patel, Y Nishizuka, Y Ono, Y Takai   +38 more
core   +3 more sources

Animal models of ischaemic stroke and characterisation of the ischaemic penumbra [PDF]

, 2018
Over the past forty years, animal models of focal cerebral ischaemia have allowed us to identify the critical cerebral blood flow thresholds responsible for irreversible cell death, electrical failure, inhibition of protein synthesis, energy depletion ...
Arroja, Mariana M., Macrae, I. Mhairi, McCabe, Christopher, Reid, Emma   +3 more
core   +1 more source

Attempt to establish an experimental animal model of moyamoya disease using immuno-embolic material--histological changes of the arterial wall resulting from immunological reaction in cats. [PDF]

, 2003
In this study, we investigated the relationship between intimal thickening of the internal carotid artery (ICA) and immunological reaction, and between occlusion of the ICA and development of basal collateral vessels in moyamoya disease.
Kamata, Ichiro, Ohmoto, Takashi, Terai, Yoshinori   +2 more
core   +1 more source

Computed microtomography visualization and quantification of mouse ischemic brain lesion by nonionic radio contrast agents. [PDF]

, 2001
AIM: To explore the possibility of brain imaging by microcomputed tomography (microCT) using x-ray contrasting methods to visualize mouse brain ischemic lesions after middle cerebral artery occlusion (MCAO).
A. Bouajjani, B. Steffen, E.A. Emerson, J. Esparza, J. Esparza, J. Esparza, O. Burkart, T. Ball   +7 more
core   +7 more sources

CT perfusion as a selection tool for mechanical thrombectomy, a single-centre study [PDF]

, 2020
Background: Recently, CT perfusion (CTP) has been proposed as a selection tool for stroke patients to be treated with endovascular thrombectomy.
De Muynck, Emilie, Defreyne, Luc, Dhondt, Elisabeth, Hemelsoet, Dimitri, Huybrechts, Vincent, Vanlangenhove, Peter   +5 more
core   +1 more source

A horse, a horse, my kingdom for a horse. Saddle thrombosis of carotid bifurcation in acute stroke [PDF]

, 2012
Background: Saddle thrombosis is less frequently detected in carotid arteries than in peripheral arterial embolism. The clot and the distal vessel patency have to be promptly recognized in these cases, because if the carotid vessel is open distally ...
DI PIERO, Vittorio, Edoardo Vicenzini, GIANNONI, Maria Fabrizia, LENZI, Gian Luigi, Maria Chiara Ricciardi, SIRIMARCO, GAIA, TOSCANO M.   +6 more
core   +1 more source